Evidence map›Paper›PMID 30627698›Full record

ArticleAntibody therapeutics2019

Construction and next-generation sequencing analysis of a large phage-displayed V

Mingqian Feng, Hejiao Bian, Xiaolin Wu, Tianyun Fu, Ying Fu, Jessica Hong, Bryan D Fleming, Martin F Flajnik, Mitchell Ho

Open access · goldAbstract read
In one paragraph

Article in Antibody therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Construction of Naïve and Immune Human Fab Phage Display Library.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Site-Specifically Conjugated Single-Domain Antibody Successfully Identifies Glypican-3-Expressing Liver Cancer by Immuno-PET.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  19. Identification of nurse shark VFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mingqian FengLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Hejiao BianLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Xiaolin WuCancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Tianyun FuLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Ying FuLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Jessica HongLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Bryan D FlemingLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Martin F FlajnikDepartment of Microbiology and Immunology, University of Maryland Baltimore School of Medicine, Baltimore, MD, USA.
Mitchell HoLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
National Cancer Institute · USCenter for Cancer Research · USLeidos (United States) · USUniversity of Maryland, Baltimore · US

Funding

Antibody Engineering ProgramZICBC011891 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HO, MITCHELL · 2019 to 2025
$4.5M
Antibody Therapy of CancerZ01BC010891 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HO, MITCHELL · 2008 to 2008
$56k
CCR NIH HHS HHSN261200800001CIntramural NIH HHS Z01 BC010891NCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

gene library constructionnext-generation sequencingphage displayshark VNARsingle-domain antibody

Identifiers

PMID30627698
PMCPMC6312525
OpenAlexW2899623314

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.