Evidence map›Paper›PMID 30627692›Full record

ArticleEnvironmental epidemiology (Philadelphia, Pa.)2018

Prenatal air pollution exposure, smoking, and uterine vascular resistance.

Zuelma A Contreras, Julia E Heck, Pei-Chen Lee, Xin Cui, Calvin J Hobel, Carla Janzen, Fred Lurmann, Beate Ritz

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental epidemiology (Philadelphia, Pa.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Ambient air pollution and adverse birth outcomes: A review of underlying mechanisms.BJOG : an international journal of obstetrics and gynaecology · 2024
    Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Zuelma A ContrerasDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, USA.
Julia E HeckDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, USA.
Pei-Chen LeeDepartment of Health Care Management, College of Health Technology, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
Xin CuiDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, USA.
Calvin J HobelDepartment of Obstetrics, Gynecology and Pediatrics, Cedars Sinai Medical Center, Los Angeles, California, USA.
Carla JanzenDepartment of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Fred LurmannSonoma Technology, Inc., Petaluma, California, USA.
Beate RitzDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, USA.
University of California, Los Angeles · USCedars-Sinai Medical Center · USMinistry of Health and Welfare · TWSonoma Technology (United States) · US

Funding

UCLA CANCER EPIDEMIOLOGY TRAINING PROGRAMT32CA009142 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHANG, ZUO-FENG · 1986 to 2024
$6.3M
Imaging Innovations for Placental Assessment in Response to Environmental PollutionU01HD087221 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DEVASKAR, SHERIN U, JANZEN, CARLA · 2015 to 2015
$4.3M
Traffic-Related Air Pollution and Ultrasound Measures of Fetal GrowthR03ES017314 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TURNER, MICHELLE WILHELM · 2009 to 2010
$195k
NCI NIH HHS T32 CA009142NICHD NIH HHS U01 HD087221NIEHS NIH HHS R03 ES017314
6 · The paper itself

Abstract

backgroundPrenatal exposure to air pollution and smoking increases the risk of pregnancy complications and adverse birth outcomes, but pathophysiologic mechanisms are still debated. Few studies to date have examined the influence of air pollution on uterine vascular resistance and no studies have examined the independent impact of these exposures. We aimed to assess the impact of prenatal exposure to traffic-related air pollution and smoking on uterine vascular resistance.

methodsOur study included 566 pregnant women recruited between 1993 and 1996 in Los Angeles who completed visits at three gestational ages. Information on smoking was collected and uterine vascular resistance was measured at each visit by Doppler ultrasound. We calculated three resistance indices: the resistance index (RI), the pulsatility index (PI), and the systolic/diastolic (S/D) ratio. We estimated exposure to NO

resultsLUR-derived NO

conclusionOur results suggest that uterine vascular resistance is a mechanism underlying the association between smoking and air pollution, and adverse birth outcomes.

Indexed as

air pollutionnitrogen dioxidenitrogen oxideresistance indexsmokinguterine vascular resistance

Identifiers

PMID30627692
PMCPMC6322670
OpenAlexW2809219483

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.