Evidence map›Paper›PMID 30627559›Full record

ArticleBioMed research international2018

SIRT7 Regulates the Vascular Smooth Muscle Cells Proliferation and Migration via Wnt/

Jianghua Zheng, Kai Chen, Haifei Wang, Zhilong Chen, Yong Xi, Hongshun Yin, Kun Lai, Yujuan Liu

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 76 citations in OpenAlex.

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  11. The sirtuin family in health and disease.Signal transduction and targeted therapy · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jianghua ZhengDepartment of Vascular Surgery, Affiliated Hospital of North Sichuan Medical College, China.
Kai ChenDepartment of Vascular Surgery, Affiliated Hospital of North Sichuan Medical College, China.
Haifei WangDepartment of Vascular Surgery, Affiliated Hospital of North Sichuan Medical College, China.
Zhilong ChenDepartment of Vascular Surgery, Affiliated Hospital of North Sichuan Medical College, China.
Yong XiDepartment of Vascular Surgery, Affiliated Hospital of North Sichuan Medical College, China.
Hongshun YinDepartment of Vascular Surgery, Affiliated Hospital of North Sichuan Medical College, China.
Kun LaiDepartment of Vascular Surgery, Affiliated Hospital of North Sichuan Medical College, China.
Yujuan LiuDepartment of Gynaecology and Obstetrics, Affiliated Hospital of North Sichuan Medical College, China.ORCID 0000-0003-1980-1871
Affiliated Hospital of North Sichuan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A huge amount of evidence indicates that sirtuin 7 (SIRT7), a key mediator of many cellular activities, plays a crucial role in the pathogenesis of various diseases. However, little is known about the role of SIRT7 in atherosclerosis. This study investigated the potential role of SIRT7 in regulating the proliferation and migration of human vascular smooth muscle cells (HAVSMCs) and its possible molecular mechanism. In this study, human vascular smooth muscle cells (HAVSMCs) were induced by oxidized low-density lipoprotein (ox-LDL) to establish atherosclerosis (AS) cell model. Immunofluorescence staining and Western blot were used to detect the level of

Indexed as

Cell CycleCell MovementWnt Signaling PathwayAtherosclerosisbeta CateninCell LineGene Expression RegulationHumansMuscle, Smooth, VascularMyocytes, Smooth MuscleSirtuinsbeta CateninSIRT7 protein, humanSirtuins

Identifiers

PMID30627559
PMCPMC6304541
OpenAlexW2903104110

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.