Evidence map›Paper›PMID 30627515›Full record

ArticleToxicology reports2018

Nephrotoxicity and highly active antiretroviral therapy: Mitigating action of

Ugochukwu Offor, Edwin Coleridge Naidu, Oluwatosin Olalekan Ogedengbe, Ayoola Isaac Jegede, Aniekan Imo Peter, Onyemaechi Okpara Azu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Multidimensional Uses of Bitter Melon (Current organic synthesis · 2025
    Review
  3. Article
  4. Methanol Crude Peel Extract ofJournal of experimental pharmacology · 2024
    Article
  5. Plants (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Ugochukwu OfforDepartment of Clinical Anatomy, School of Laboratory Medicine and Medical Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, South Africa.
Edwin Coleridge NaiduDepartment of Clinical Anatomy, School of Laboratory Medicine and Medical Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, South Africa.
Oluwatosin Olalekan OgedengbeDepartment of Clinical Anatomy, School of Laboratory Medicine and Medical Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, South Africa.
Ayoola Isaac JegedeDepartment of Clinical Anatomy, School of Laboratory Medicine and Medical Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, South Africa.
Aniekan Imo PeterDepartment of Clinical Anatomy, School of Laboratory Medicine and Medical Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, South Africa.
Onyemaechi Okpara AzuDepartment of Clinical Anatomy, School of Laboratory Medicine and Medical Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, South Africa.
University of KwaZulu-Natal · ZAUniversity of Uyo · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

6-HD, 6-hydroxydopamineAIDS, acquired immune deficiency syndromeALB, albuminANOVA, analysis of varianceAREC, animal research ethics committeeBGL, blood glucose levelsBRU, Biomedical Resource UnitBUN, blood urea nitrogenBW, body weightCAT, catalaseDETAPAC, diethylenetriamine – penta acetic acidDNA, deoxyribonucleic acidDTNB, 5, 5'-dithiobis-(2-nitrobenzoic acid)GSH, reduced glutathioneHAARTHAART, highly active antiretroviral therapyH and E, haematoxylin and eosinHistopathologyHIV, human immunodeficiency virusKidneyKWBR, kidney weight body ratioKW, kidney weightLPO, lipid peroxidationM. charantia, Momordica charantiaMDA, malondialdehydeMomordica charantiaMT, Masson’s TrichomeNephrotoxicityNRTIs, nucleoside reverse transcriptase inhibitorsPAS, Periodic Acid SchiffPBS, phosphate buffer solutionPLWHA, people living with HIV and AIDSROS, reactive oxygen speciesrpm, revolutions per minuteSCr, serum creatinineSDS, sodium dodecyl sulfateSD, standard deviationSOD, superoxide dismutaseSprague-Dawley ratsTBARS, thiobarbituric acid reactive substancesTCA, trichloroacetic acidUKZN, University of KwaZulu Natal

Identifiers

PMID30627515
PMCPMC6319328
OpenAlexW2891275050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.