Evidence map›Paper›PMID 30627396›Full record

ArticleChemical science2018

Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation.

David Montoir, Mehdi Amoura, Zine El Abidine Ababsa, T M Vishwanatha, Expédite Yen-Pon, Vincent Robert, Massimiliano Beltramo, Véronique Piller, Mouad Alami, Vincent Aucagne and 1 more

Abstract read
In one paragraph

Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Visible-Light-Mediated Synthesis of AnomericMolecules (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Late-stage C(spChemical science · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

David MontoirBioCIS , Univ. Paris-Sud , CNRS , Univ. Paris-Saclay , Châtenay-Malabry , France . Email: samir.messaoudi@u-psud.fr ; Tel: +33 0146835887.
Mehdi AmouraCentre de Biophysique Moléculaire , CNRS , Orléans , France . Email: aucagne@cnrs-orleans.fr ; Tel: +33 0238255577.
Zine El Abidine AbabsaBioCIS , Univ. Paris-Sud , CNRS , Univ. Paris-Saclay , Châtenay-Malabry , France . Email: samir.messaoudi@u-psud.fr ; Tel: +33 0146835887.
T M VishwanathaCentre de Biophysique Moléculaire , CNRS , Orléans , France . Email: aucagne@cnrs-orleans.fr ; Tel: +33 0238255577.
Expédite Yen-PonBioCIS , Univ. Paris-Sud , CNRS , Univ. Paris-Saclay , Châtenay-Malabry , France . Email: samir.messaoudi@u-psud.fr ; Tel: +33 0146835887.
Vincent RobertUMR Physiologie de la Reproduction et des Comportements , INRA , CNRS , Univ. Tours , IFCE , Nouzilly , France.
Massimiliano BeltramoUMR Physiologie de la Reproduction et des Comportements , INRA , CNRS , Univ. Tours , IFCE , Nouzilly , France.
Véronique PillerCentre de Biophysique Moléculaire , CNRS , Orléans , France . Email: aucagne@cnrs-orleans.fr ; Tel: +33 0238255577.
Mouad AlamiBioCIS , Univ. Paris-Sud , CNRS , Univ. Paris-Saclay , Châtenay-Malabry , France . Email: samir.messaoudi@u-psud.fr ; Tel: +33 0146835887.ORCID 0000-0003-4601-462X
Vincent AucagneCentre de Biophysique Moléculaire , CNRS , Orléans , France . Email: aucagne@cnrs-orleans.fr ; Tel: +33 0238255577.ORCID 0000-0002-2647-0188
Samir MessaoudiBioCIS , Univ. Paris-Sud , CNRS , Univ. Paris-Saclay , Châtenay-Malabry , France . Email: samir.messaoudi@u-psud.fr ; Tel: +33 0146835887.ORCID 0000-0002-4994-9001

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe herein a Pd-catalyzed methodology for the thioglycoconjugation of iodoaryl peptides and aminoacids. This operationally simple process occurs under semi-aqueous conditions and displays wide substrate scope. The strategy has been successfully applied to both the thioglycosylation of unprotected peptides and the generation of thioglyco-aminoacid building blocks, including those suitable for solid phase peptide synthesis. To demonstrate the broad potential of this technique for late stage functionalization, we successfully incorporated challenging unprotected β-

Identifiers

PMID30627396
PMCPMC6295873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.