Evidence map›Paper›PMID 30627309›Full record

ArticleThe Pan African medical journal2018

Descriptive analysis of colorectal cancer in Zambia, Southern Africa using the National Cancer Disease Hospital Database.

Akwi Wasi Asombang, Richard Madsen, Michelo Simuyandi, Gilbert Phiri, Matthew Bechtold, Jamal Ahmad Ibdah, Kennedy Lishimpi, Lewis Banda

Abstract read
In one paragraph

Article in The Pan African medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Akwi Wasi AsombangDivision of Gastroenterology, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Richard MadsenDepartment of Statistics, University of Missouri-Columbia School of Medicine, Missouri, USA.
Michelo SimuyandiCenter of Infectious Disease Research in Zambia (CIDRZ), Lusaka, Zambia.
Gilbert PhiriCancer Disease Hospital (CDH), Lusaka, Zambia.
Matthew BechtoldDivision of Gastroenterology and Hepatology, University of Missouri-Columbia School of Medicine, Missouri, USA.
Jamal Ahmad IbdahDivision of Gastroenterology and Hepatology, University of Missouri-Columbia School of Medicine, Missouri, USA.
Kennedy LishimpiCancer Disease Hospital (CDH), Lusaka, Zambia.
Lewis BandaCancer Disease Hospital (CDH), Lusaka, Zambia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionColon cancer is preventable. There is a plethora of data regarding epidemiology and screening guidelines, however this data is sparse from the African continent. Objective: we aim to evaluate the trends of colorectal cancer (CRC) in a native African population based on age at diagnosis, gender and stage at diagnosis.

methodsWe conducted a retrospective analysis of the Cancer Disease Hospital (CDH) registry in Zambia, Southern Africa.

results377 charts were identified in the CDH registry between 2007 and 2015, of which 234 were included in the final analysis. The mean age at diagnosis was 48.6 years and 62% are males. Using descriptive analysis for patterns: mode of diagnosis was surgical in 195 subjects (84%), histology adenocarcinoma in 225 (96.5%), most common location is rectum 124 (53%) followed by sigmoid 31 (13.4%), and cecum 26 (11%). 122 subjects (54%) were stage 4 at diagnosis. Using the Spearman rank correlation, we see no association between year and stage at diagnosis (p = 0.30) or year and age at diagnosis (p = 0.92).

conclusionColorectal cancer was diagnosed at a young age and late stage in the Zambian patients.

Indexed as

AdenocarcinomaAdolescentAdultAgedAged, 80 and overAge of OnsetCancer Care FacilitiesChildColorectal NeoplasmsDatabases, FactualFemaleHumansMaleMass ScreeningMiddle AgedNeoplasm Stagingcancer in Africacolon cancerColorectal cancernon-communicable diseasesrectal cancer

Identifiers

PMID30627309
PMCPMC6307926

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.