Evidence map›Paper›PMID 30627225›Full record

ArticleDisease markers2018

Correlation of Triiodothyronine Level with In-Hospital Cardiac Function and Long-Term Prognosis in Patients with Acute Myocardial Infarction.

Jianqing She, Jiahao Feng, Yangyang Deng, Lizhe Sun, Yue Wu, Manyun Guo, Xiao Liang, Jingjin Li, Yulong Xia, Zuyi Yuan

Abstract read
In one paragraph

Article in Disease markers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jianqing SheCardiovascular Department, First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710048, China.
Jiahao FengCardiovascular Department, First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710048, China.
Yangyang DengCardiovascular Department, First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710048, China.
Lizhe SunCardiovascular Department, First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710048, China.
Yue WuCardiovascular Department, First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710048, China.
Manyun GuoCardiovascular Department, First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710048, China.
Xiao LiangCardiovascular Department, First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710048, China.
Jingjin LiCardiovascular Department, First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710048, China.
Yulong XiaCardiovascular Department, First Affiliated Hospital of Peking University, Beijing 100005, China.
Zuyi YuanCardiovascular Department, First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710048, China.ORCID 0000-0003-0387-4398

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe pathophysiologic mechanism of how thyroid function is related to the development and prognosis of acute myocardial infarction (AMI) remains under explored, and there has been a lack of clinical investigations. In this study, we investigate the relationship between triiodothyronine (T3) level and cardiac ejection fraction (EF) as well as probrain natriuretic peptide (NT-proBNP) on admission and subsequent prognosis in AMI patients.

methodsWe measured admission thyroid function, NT-proBNP, and EF by echocardiography in 345 patients diagnosed with AMI. Simple and multiregression analyses were performed to investigate the correlation between T3 level and EF as well as NT-proBNP. Major adverse cardiovascular events (MACE), including new-onset myocardial infarction, acute heart failure, and cardiac death, were documented during the follow-up. 248 participants were separated into three groups based on T3 and free triiodothyronine (FT3) levels for survival analysis during a 2-year follow-up.

results345 patients diagnosed with AMI were included in the initial observational analysis. 248 AMI patients were included in the follow-up survival analysis. The T3 levels were found to be significantly positively correlated with EF (

conclusionsT3 and FT3 levels are moderately positively correlated with cardiac function on admission in AMI patients but did not predict a long-time survival rate. Further studies are needed to explain whether longer-term follow-up would further identify the prognosis effect of T3 on MACE and all-cause mortality.

Indexed as

Stroke VolumeAgedBiomarkersEchocardiographyFemaleHumansInpatientsMaleMiddle AgedMyocardial InfarctionNatriuretic Peptide, BrainPeptide FragmentsPrognosisProspective StudiesRegression AnalysisSurvival AnalysisBiomarkersNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)Triiodothyronine

Identifiers

PMID30627225
PMCPMC6304898

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.