Evidence map›Paper›PMID 30627163›Full record

ArticleInternational journal of analytical chemistry2018

Gas Chromatography Coupled to High Resolution Time-of-Flight Mass Spectrometry as a High-Throughput Tool for Characterizing Geochemical Biomarkers in Sediments.

Hector Henrique Ferreira Koolen, Clécio Fernando Klitzke, Joe Binkley, Jeffrey Patrick, Ana Cecília Rizatti de Albergaria-Barbosa, Rolf Roland Weber, Márcia Caruso Bícego, Marcos Nogueira Eberlin, Giovana Anceski Bataglion

Abstract read
In one paragraph

Article in International journal of analytical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hector Henrique Ferreira KoolenThoMSon Mass Spectrometry Laboratory, Institute of Chemistry, University of Campinas (UNICAMP), 13083-970, Campinas, SP, Brazil.ORCID 0000-0002-0181-348X
Clécio Fernando KlitzkeLECO Corporation, 49085, St. Joseph, MI, USA.
Joe BinkleyLECO Corporation, 49085, St. Joseph, MI, USA.
Jeffrey PatrickLECO Corporation, 49085, St. Joseph, MI, USA.
Ana Cecília Rizatti de Albergaria-BarbosaLaboratory of Marine Geochemistry, Geoscience Institute, Federal University of Bahia (UFBA), 40170-020, Salvador, BA, Brazil.
Rolf Roland WeberMarine Organic Chemistry Laboratory, Oceanographic Institute, University of São Paulo (USP), 05508-120, São Paulo, SP, Brazil.
Márcia Caruso BícegoMarine Organic Chemistry Laboratory, Oceanographic Institute, University of São Paulo (USP), 05508-120, São Paulo, SP, Brazil.
Marcos Nogueira EberlinThoMSon Mass Spectrometry Laboratory, Institute of Chemistry, University of Campinas (UNICAMP), 13083-970, Campinas, SP, Brazil.
Giovana Anceski BataglionThoMSon Mass Spectrometry Laboratory, Institute of Chemistry, University of Campinas (UNICAMP), 13083-970, Campinas, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The performance of gas chromatography coupled to high-resolution time-of-flight mass spectrometry (GC-HRTofMS) for characterizing geochemical biomarkers from sediment samples was evaluated. Two approaches to obtain the geochemical biomarkers were tested: (1) extraction with organic solvent and subsequent derivatization and (2) in-situ derivatization thermal desorption. Results demonstrated that both approaches can be conveniently applied for simultaneous characterization of many geochemical biomarkers (alkanes, alkanols, sterols, and fatty acids), avoiding conventional time-consuming purification procedures. GC-HRTofMS reduces both sample preparation time and the number of chromatographic runs compared to traditional methodologies used in organic geochemistry. Particularly, the approach based on in-situ derivatization thermal desorption represents a very simple method that can be performed in-line employing few milligrams of sediment, eliminating the need for any sample preparation and solvent use. The high resolving power (

Identifiers

PMID30627163
PMCPMC6304594

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.