Evidence map›Paper›PMID 30627063›Full record

ArticleContrast media & molecular imaging2018

Prostate Osteoblast-Like Cells: A Reliable Prognostic Marker of Bone Metastasis in Prostate Cancer Patients.

Manuel Scimeca, Nicoletta Urbano, Rita Bonfiglio, Sarah Natalia Mapelli, Carlo Vittorio Catapano, Giuseppina Maria Carbone, Sara Ciuffa, Mario Tavolozza, Orazio Schillaci, Alessandro Mauriello and 1 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. ZNF750: A Novel Prognostic Biomarker in Metastatic Prostate Cancer.International journal of molecular sciences · 2023
    Article
  10. Preparation, Optimisation, and In Vitro Evaluation of [Molecules (Basel, Switzerland) · 2022
    Article
  11. [Molecular and cellular biochemistry · 2022
    Article
  12. Article
  13. Review
  14. Osteoblast Dysfunction in Non-Hereditary Sclerosing Bone Diseases.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Journal of clinical medicine · 2019
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Manuel ScimecaDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", Via Montpellier 1, Rome 00133, Italy.ORCID 0000-0003-0585-1309
Nicoletta UrbanoNuclear Medicine, Policlinico "Tor Vergata", Rome, Italy.
Rita BonfiglioDepartment of Experimental Medicine and Surgery, University "Tor Vergata", Via Montpellier 1, Rome 00133, Italy.ORCID 0000-0003-4172-2977
Sarah Natalia MapelliUniversità della Svizzera Italiana (USI), Institute of Oncology Research (IOR), Via Vela 6, Bellinzona, Switzerland.
Carlo Vittorio CatapanoUniversità della Svizzera Italiana (USI), Institute of Oncology Research (IOR), Via Vela 6, Bellinzona, Switzerland.
Giuseppina Maria CarboneUniversità della Svizzera Italiana (USI), Institute of Oncology Research (IOR), Via Vela 6, Bellinzona, Switzerland.
Sara CiuffaDepartment of Experimental Medicine and Surgery, University "Tor Vergata", Via Montpellier 1, Rome 00133, Italy.
Mario TavolozzaNuclear Medicine, Policlinico "Tor Vergata", Rome, Italy.
Orazio SchillaciDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", Via Montpellier 1, Rome 00133, Italy.
Alessandro MaurielloDepartment of Experimental Medicine and Surgery, University "Tor Vergata", Via Montpellier 1, Rome 00133, Italy.ORCID 0000-0002-7351-5676
Elena BonannoDepartment of Experimental Medicine and Surgery, University "Tor Vergata", Via Montpellier 1, Rome 00133, Italy.ORCID 0000-0002-0222-0141
University of Rome Tor Vergata · ITInstitute of Oncology Research · CHPoliclinico Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main aim of this study was to investigate the putative association among the presence of prostate cancer cells, defined as prostate osteoblast-like cells (POLCs), and showing the expression of typical morphological and molecular characteristics of osteoblasts, the development of bone metastasis within 5 years of diagnosis, and the uptake of 18F-choline evaluated by PET/CT analysis. To this end, prostate biopsies (

Indexed as

Bone NeoplasmsCalcification, PhysiologicCalcinosisCell DifferentiationCell ShapeCholineEpithelial-Mesenchymal TransitionFluorine RadioisotopesHumansMaleMiddle AgedOsteoblastsPositron Emission Tomography Computed TomographyPrognosisProstatic NeoplasmsCholineFluorine-18Fluorine Radioisotopes

Identifiers

PMID30627063
PMCPMC6305022
OpenAlexW2905428993

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.