ArticleProceedings. American Statistical Association. Annual Meeting
Ex-Vivo Modeling for Heritability Assessment and Genetic Mapping in Pharmacogenomics.
Article in Proceedings. American Statistical Association. Annual Meeting. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Application of next generation sequencing to CEPH cell lines to discover variants associated with FDA approved chemotherapeutics.BMC research notes · 2014Article
- Lymphoblastoid cell lines models of drug response: successes and lessons from this pharmacogenomic model.Current molecular medicine · 2014Article
- A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.Pharmacogenetics and genomics · 2012Article
- A comparison of association methods for cytotoxicity mapping in pharmacogenomics.Frontiers in genetics · 2011Article
- Nonlinear Dose-Response Modeling of High-Throughput Screening Data Using an Evolutionary Algorithm.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
The investigation of genetic factors that determine differential drug response is a key goal of pharmacogenomics (PGX), and relies on the often-untested assumption that differential response is heritable. While limitations in traditional study design often prohibit heritability (h
Indexed as
Identifiers
30627054PMC6322852W3024348747What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.