Evidence map›Paper›PMID 30627028›Full record

ArticleKorean journal of radiology2019

Fat Quantification in the Vertebral Body: Comparison of Modified Dixon Technique with Single-Voxel Magnetic Resonance Spectroscopy.

Sang Hyup Lee, Hye Jin Yoo, Seung-Man Yu, Sung Hwan Hong, Ja-Young Choi, Hee Dong Chae

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Korean journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Association of proton-density fat fraction with osteoporosis: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Pooled it
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  4. Biochemical and microenvironmental characterization of the disc-vertebra complex in non-specific low back pain using non-fat-saturation multi-slice CEST MRI.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  15. Quantitative analysis of vertebral fat fraction and R2BMC musculoskeletal disorders · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sang Hyup LeeDepartment of Radiology, Seoul National University Hospital, Seoul, Korea.ORCID 0000-0002-6773-2965
Hye Jin YooDepartment of Radiology, Seoul National University Hospital, Seoul, Korea.ORCID 0000-0002-9704-7870
Seung-Man YuDepartment of Radiological Science, College of Health Science, Gimcheon University, Gimcheon, Korea.
Sung Hwan HongDepartment of Radiology, Seoul National University Hospital, Seoul, Korea.
Ja-Young ChoiDepartment of Radiology, Seoul National University Hospital, Seoul, Korea.
Hee Dong ChaeDepartment of Radiology, Seoul National University Hospital, Seoul, Korea.
Seoul National University · KRGimcheon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To compare the lumbar vertebral bone marrow fat-signal fractions obtained from six-echo modified Dixon sequence (6-echo m-Dixon) with those from single-voxel magnetic resonance spectroscopy (MRS) in patients with low back pain. Materials and Methods: Vertebral bone marrow fat-signal fractions were quantified by 6-echo m-Dixon (repetition time [TR] = 7.2 ms, echo time (TE) = 1.21 ms, echo spacing = 1.1 ms, total imaging time = 50 seconds) and single-voxel MRS measurements in 25 targets (23 normal bone marrows, two focal lesions) from 24 patients. The point-resolved spectroscopy sequence was used for localized single-voxel MRS (TR = 3000 ms, TE = 35 ms, total scan time = 1 minute 42 seconds). A 2 × 2 × 1.5 cm Results: There was a strong correlation between m-Dixon and MRS-based fat-signal fractions (slope = 0.86, R Conclusion: Given its excellent agreement with single-voxel-MRS, 6-echo m-Dixon can be used for visual and quantitative evaluation of vertebral bone marrow fat in daily practice.

Indexed as

Adipose TissueAdultAgedBone MarrowFemaleFractures, CompressionHumansLow Back PainLumbar VertebraeMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMiddle AgedSpinal FracturesTriglyceridesTriglyceridesFat quantificationModified DixonMR spectroscopyVertebra

Identifiers

PMID30627028
PMCPMC6315074
OpenAlexW2907184985

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.