ArticleScientific reports2019
The ecdysone receptor complex is essential for the reproductive success in the female desert locust, Schistocerca gregaria.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 73 citations in OpenAlex.
- Roles of the chemosensory protein RpCSP8 in reproduction and feeding behavior of sexual and non-sexual female of Rhopalosiphum padi.Insect science · 2026Article
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- Molecular Characterization and Expression of the Ecdysone Receptor and Ultraspiracle Genes in the Wheat Blossom Midge,Insects · 2025Article
- Juvenile Hormone and Ecdysteroids Facilitate the Adult Reproduction Through theInternational journal of molecular sciences · 2025Article
- 20-Hydroxyecdysone Mediates Reproductive Diapause inInternational journal of molecular sciences · 2024Article
- An evolutionarily conserved pathway mediated by neuroparsin-A regulates reproductive plasticity in ants.PLoS biology · 2024Article
- Mining gene expression data for rational identification of novel drug targets and vaccine candidates against the cattle tick, Rhipicephalus microplus.Experimental & applied acarology · 2023Article
- The Intricate Role of Ecdysis Triggering Hormone Signaling in Insect Development and Reproductive Regulation.Insects · 2023Review
- Crosstalk between Nutrition, Insulin, Juvenile Hormone, and Ecdysteroid Signaling in the Classical Insect Model,International journal of molecular sciences · 2022Article
- Knockdown of theInternational journal of molecular sciences · 2022Article
- Cyromazine Effects the Reproduction ofInsects · 2022Article
- Cyromazine affects the ovarian germ cells ofFrontiers in physiology · 2022Article
- Review
- Research Progress on Oviposition-Related Genes in Insects.Journal of insect science (Online) · 2020Review
- RNAi-Mediated Knockdown of Transcription Factor E93 in Nymphs of the Desert Locust (International journal of molecular sciences · 2020Article
- Precocious Downregulation of Krüppel-Homolog 1 in the Migratory Locust,International journal of molecular sciences · 2020Article
- Transcriptome analysis of the almond moth, Cadra cautella, female abdominal tissues and identification of reproduction control genes.BMC genomics · 2019Article
- Juvenile Hormone receptor Met is essential for ovarian maturation in the Desert Locust, Schistocerca gregaria.Scientific reports · 2019Article
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4 authors at 1 institution in 1 country.
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Abstract
Ecdysteroid hormones influence the development and reproduction of arthropods by binding a heterodimeric complex of nuclear receptors, the ecdysone receptor (EcR) and the retinoid-X-receptor/ultraspiracle (RXR/USP). Here, we report on the in vivo role(s) of the ecdysone receptor complex, SchgrEcR/SchgrRXR, in the female reproductive physiology of a major phytophagous pest insect, i.e. the desert locust, Schistocerca gregaria. Tissue and temporal distribution profiles were analysed during the first gonadotrophic cycle of adult female locusts. RNA interference was used as a reverse genetics tool to investigate the in vivo role of the ecdysone receptor complex in ovarian maturation, oogenesis, fertility and fecundity. We discovered that silencing the ecdysone receptor complex in S. gregaria resulted in impaired ovulation and oviposition, indicative for a crucial role of this complex in chorion formation. We also found evidence for a feedback of SchgrEcR/SchgrRXR on juvenile hormone biosynthesis by the corpora allata. Furthermore, we observed a tissue-dependent effect of the SchgrEcR/SchgrRXR knockdown on the transcript levels of the insulin receptor and neuroparsin 3 and 4. The insulin receptor transcript levels were upregulated in the brain, but not the fat body and gonads. Neuroparsins 3 and 4 transcript levels were down regulated in the brain and fat body, but not in the gonads.
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