Evidence map›Paper›PMID 30626819›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Pazopanib Confers a Progression-free Survival in a Patient with Ewing's Sarcoma/Primitive Neuroectodermal Tumor of the Lung.

Ayako Takigami, Hideaki Yamasawa, Ayako Kurosaki, Noritaka Sakamoto, Tsugitoshi Onuki, Naoko Mato, Kenji Tetsuka, Shunsuke Endo, Toshiro Niki, Masashi Bando and 1 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Ewing sarcoma presenting in the lung: a case report.Journal of medical case reports · 2024
    Article
  2. Activity of pazopanib inOncoscience · 2023
    Article
  3. Article
  4. A rare radiotherapy-sensitive primitive neuroectodermal tumor withThe Journal of international medical research · 2022
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Primary Ewing's sarcoma of the lung: a rare case report.Indian journal of thoracic and cardiovascular surgery · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ayako TakigamiDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Hideaki YamasawaDepartment of Pulmonary Medicine, International University of Health and Welfare, Japan.
Ayako KurosakiDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Noritaka SakamotoDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Tsugitoshi OnukiDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Naoko MatoDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Kenji TetsukaDepartment of General Thoracic Surgery, Jichi Medical University, Japan.
Shunsuke EndoDepartment of General Thoracic Surgery, Jichi Medical University, Japan.
Toshiro NikiDepartment of Integrative Pathology, Jichi Medical University, Japan.
Masashi BandoDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Koichi HagiwaraDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Jichi Medical University · JPInternational University of Health and Welfare · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ewing's sarcoma (ES)/primitive neuroectodermal tumors (PNETs) are highly malignant neoplasms that usually affect the bones and soft tissues in children and young adults. ES/PNET of the lung is very rare and is associated with a poor prognosis. We herein report a case of ES/PNET of the left lung in a 45-year-old man. He was treated with neoadjuvant chemotherapy and pneumonectomy, but unfortunately his disease recurred 1.5 months after surgery. He was started on pazopanib, which resulted in a five-month progression-free survival. To our knowledge, this is the first demonstration of pazopanib efficacy in ES/PNET of the lung.

Indexed as

Antineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsChemotherapy, AdjuvantFatal OutcomeHumansIndazolesLung NeoplasmsMaleMiddle AgedNeoplasm Recurrence, LocalNeuroectodermal Tumors, PrimitivePneumonectomyProgression-Free SurvivalPyrimidinesSarcoma, EwingSulfonamidesAntineoplastic AgentsIndazolespazopanibPyrimidinesSulfonamidesEwing's sarcomapazopanibprimitive neuroectodermal tumors

Identifiers

PMID30626819
PMCPMC6543224
OpenAlexW2909664027

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.