Evidence map›Paper›PMID 30626735›Full record

ArticleThe Journal of biological chemistry2019

Ctp1 protein-DNA filaments promote DNA bridging and DNA double-strand break repair.

Sara N Andres, Zimeng M Li, Dorothy A Erie, R Scott Williams

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. A conserved Ctp1/CtIP C-terminal peptide stimulates Mre11 endonuclease activity.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Article
  11. Phosphorylated CtIP bridges DNA to promote annealing of broken ends.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  12. CtIP promotes the motor activity of DNA2 to accelerate long-range DNA end resection.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  13. Article
  14. Review
  15. Seeing is believing: DNA zipping promotes DNA repair.The Journal of biological chemistry · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sara N AndresFrom the Genome Integrity and Structural Biology Laboratory, NIEHS, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709.ORCID 0000-0002-4795-2856
Zimeng M Lithe Department of Physics and Astronomy, University of North Carolina, Chapel Hill, North Carolina 27695, and.
Dorothy A Eriethe Department of Chemistry, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599 derie@unc.edu.
R Scott WilliamsFrom the Genome Integrity and Structural Biology Laboratory, NIEHS, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, williamsrs@niehs.nih.gov.ORCID 0000-0002-4610-8397
National Institutes of Health · USUniversity of North Carolina at Chapel Hill · US

Funding

Structural Biology of Genome Maintenance and DNA repairZIAES102765 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WILLIAMS, ROBERT · 2010 to 2025
$35.2M
Integrative single molecule studies: DNA repair and technology developmentR35GM127151 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DOROTHY A ERIE · 2018 to 2026
$4.6M
Structure Function Studies of DNA Mismatch RepairR01GM079480 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ERIE, DOROTHY A · 2007 to 2017
$2.7M
Quantitative analysis of transient DNA repair processes in vivoR01GM109832 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BRUSTAD, ERIC MICHAEL, ERIE, DOROTHY A · 2014 to 2017
$1.0M
Mechanistic studies of DNA repair and damage responseR01GM080294 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ERIE, DOROTHY A · 2009 to 2010
$565k
NIGMS NIH HHS R01 GM079480NIGMS NIH HHS R01 GM080294NIGMS NIH HHS R01 GM109832NIGMS NIH HHS R35 GM127151
6 · The paper itself

Abstract

The Ctp1 protein in

Indexed as

DNA Breaks, Double-StrandedDNA RepairDNA-Binding ProteinsDNA, FungalGenome, FungalModels, MolecularMutationProtein BindingProtein DomainsProtein FoldingProtein MultimerizationSchizosaccharomycesSchizosaccharomyces pombe ProteinsCtp1 protein, S pombeDNA-Binding ProteinsDNA, FungalSchizosaccharomyces pombe Proteinsatomic force microscopy (AFM)chromosome damageCtIPCtp1DNA-binding proteinDNA bridgingDNA repairhomologous recombinationSae2Schizosaccharomyces pombestructural biology

Identifiers

PMID30626735
PMCPMC6398140
OpenAlexW2909940569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.