Evidence map›Paper›PMID 30626686›Full record

ArticleJournal of virology2019

Viral Replicative Capacity, Antigen Availability via Hematogenous Spread, and High T

Preethi Eldi, Geeta Chaudhri, Stephen L Nutt, Timothy P Newsome, Gunasegaran Karupiah

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Strong influenza-induced TProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  5. Article
  6. Follicular regulatory T cells: a novel target for immunotherapy?Clinical & translational immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Preethi EldiJohn Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia.
Geeta ChaudhriJohn Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia.
Stephen L NuttThe Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Timothy P NewsomeSchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.
Gunasegaran KarupiahJohn Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia Guna.Karupiah@utas.edu.au.ORCID 0000-0001-6306-4405
Australian National University · AUThe University of Melbourne · AUThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Live viral vaccines elicit protective, long-lived humoral immunity, but the underlying mechanisms through which this occurs are not fully elucidated. Generation of affinity matured, long-lived protective antibody responses involve close interactions between T follicular helper (T

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ViralAntibody FormationAntigensB-LymphocytesCell DifferentiationCell LineChlorocebus aethiopsDogsGerminal CenterImmunity, HumoralMadin Darby Canine Kidney CellsMesocricetusMiceMice, Inbred C57BLAntibodies, NeutralizingAntibodies, ViralAntigensVaccines, Attenuatedgerminal center B cellshematogenous viral spreadinactivated vaccinesinfluenza A viruseslive vaccineslong-lived antibody responseneutralizing antibodiesorthopoxvirusesT follicular helper cellsT follicular regulatory cells

Identifiers

PMID30626686
PMCPMC6401457
OpenAlexW2910267463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.