ArticleJournal of virology2019
Establishment of a Novel Humanized Mouse Model To Investigate
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In one paragraph
Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 38 citations in OpenAlex.
- Enhancing HIV-1-specific CAR-T cell functional activity by treatment with a novel cytokine-based scaffold with IL-15 superagonist and TGF-β-neutralizing activity.Journal of virology · 2026Article
- HIV transgenic mouse monocytes display increasedJournal of virology · 2026Article
- The application of experimental models for the drug discovery for digestive tumors.Molecular cancer · 2026Review
- Multifaceted B cell response to transient HIV viremia in elite controllers.PLoS pathogens · 2026Article
- Human Immune System Reconstitution in NOD/Shi-Life (Basel, Switzerland) · 2025Article
- Melanoma in people living with HIV: Immune landscape dynamics and the role of immuno- and antiviral therapies.Cancer metastasis reviews · 2024Review
- Review
- Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIVNature communications · 2024Article
- Broadly neutralizing antibodies for HIV prevention: a comprehensive review and future perspectives.Clinical microbiology reviews · 2024Review
- Potential Perturbations of Critical Cancer-regulatory Genes in Triple-Negative Breast Cancer Cells Within the Humanized Microenvironment of Patient-derived Xenograft Models.Journal of breast cancer · 2024Article
- HIV-1 infection of genetically engineered iPSC-derived central nervous system-engrafted microglia in a humanized mouse model.Journal of virology · 2023Article
- Current Advances in Humanized Mouse Models for Studying NK Cells and HIV Infection.Microorganisms · 2023Review
- Humanized Mice for Studies of HIV-1 Persistence and Elimination.Pathogens (Basel, Switzerland) · 2023Review
- The Humanized Mouse Model: What Added Value Does It Offer for HIV Research?Pathogens (Basel, Switzerland) · 2023Review
- Baseline and time-updated factors in preclinical development of anionic dendrimers as successful anti-HIV-1 vaginal microbicides.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2022Review
- T cell receptor-targeted immunotherapeutics drive selective in vivo HIV- and CMV-specific T cell expansion in humanized mice.The Journal of clinical investigation · 2021Article
- A participant-derived xenograft model of HIV enables long-term evaluation of autologous immunotherapies.The Journal of experimental medicine · 2021Article
- Antibodies for Human Immunodeficiency Virus-1 Cure Strategies.The Journal of infectious diseases · 2021Review
- TLR-Agonist Mediated Enhancement of Antibody-Dependent Effector Functions as Strategy For an HIV-1 Cure.Frontiers in immunology · 2021Review
- μ-Lat: A mouse model to evaluate human immunodeficiency virus eradication strategies.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 2 countries.
Nina C FlerinDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Ariola BardhiDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Jian Hua ZhengDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Maria KoromDepartment of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, DC, USA.
Joy FolkvordDivision of Infectious Diseases, Department of Medicine, University of Arizona, Tucson, Arizona, USA.
Colin KovacsMaple Leaf Medical Clinic, Toronto, Ontario, Canada.
Erika BenkoMaple Leaf Medical Clinic, Toronto, Ontario, Canada.
Ronald TruongDepartment of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, DC, USA.
Talia MotaDepartment of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, DC, USA.
Elizabeth ConnickDivision of Infectious Diseases, Department of Medicine, University of Arizona, Tucson, Arizona, USA.
R Brad JonesDepartment of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, DC, USA.
Rebecca M LynchDepartment of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, DC, USA.
Harris GoldsteinDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA harris.goldstein@einstein.yu.edu.
George Washington University · USAlbert Einstein College of Medicine · USMaple Leaf Medical Clinic · CAUniversity of Arizona · US
Funding
Patient and Population Health Outcomes Research SWGP30AI124414 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI HARRIS GOLDSTEIN · 2017 to 2026
$28.3MBELIEVE: Bench to Bed Enhanced Lymphocyte Infusions to Engineer Viral EradicationUM1AI126617 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI JONES, R. BRAD, NIXON, DOUGLAS F · 2016 to 2020
$28.1MImpact of illicit drugs, HIV, and ART on neuroinflammation and BBB disruptionR01DA044584 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BERMAN, JOAN WEINBERGER, GOLDSTEIN, HARRIS · 2017 to 2021
$4.0MSystems biology analysis of in vivo impact of substance abuse on HIV infectionR01DA033788 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI GOLDSTEIN, HARRIS · 2012 to 2016
$3.0MNIAID NIH HHS P30 AI124414NIAID NIH HHS UM1 AI126617NIDA NIH HHS R01 DA033788NIDA NIH HHS R01 DA044584
Abstract
Curing HIV infection has been thwarted by the persistent reservoir of latently infected CD4
Indexed as
AnimalsAntibodies, NeutralizingCD4-Positive T-LymphocytesDisease Models, AnimalHIV-1HIV InfectionsHumansLeukocytes, MononuclearMicePhylogenySpleenViral LoadViremiaVirus LatencyVirus ReplicationAntibodies, NeutralizingHIVlatent infectionreservoir
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.