Evidence map›Paper›PMID 30626668›Full record

ArticleJournal of virology2019

Geminiviral V2 Protein Suppresses Transcriptional Gene Silencing through Interaction with AGO4.

Yunjing Wang, Yuyao Wu, Qian Gong, Asigul Ismayil, Yuxiang Yuan, Bi Lian, Qi Jia, Meng Han, Haiteng Deng, Yiguo Hong and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
9.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 58 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Yunjing Wang *MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, Tsinghua University, Beijing, China.
Yuyao Wu *MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, Tsinghua University, Beijing, China.
Qian GongMOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, Tsinghua University, Beijing, China.
Asigul IsmayilMOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, Tsinghua University, Beijing, China.
Yuxiang YuanMOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, Tsinghua University, Beijing, China.
Bi LianMOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, Tsinghua University, Beijing, China.
Qi JiaMOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, Tsinghua University, Beijing, China.
Meng HanMOE Key Laboratory of Bioinformatics and the Center of Biomedical Analysis, School of Life Sciences, Tsinghua University, Beijing, China.
Haiteng DengMOE Key Laboratory of Bioinformatics and the Center of Biomedical Analysis, School of Life Sciences, Tsinghua University, Beijing, China.
Yiguo HongResearch Center for Plant RNA Signaling, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Linda Hanley-BowdoinDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, North Carolina, USA.
Yijun QiMOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, Tsinghua University, Beijing, China qiyijun@mail.tsinghua.edu.cn yuleliu@mail.tsinghua.edu.cn.
Yule LiuMOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Center for Plant Biology, Tsinghua University, Beijing, China qiyijun@mail.tsinghua.edu.cn yuleliu@mail.tsinghua.edu.cn.
Tsinghua University · CNCenter for Life Sciences · CNHangzhou Normal University · CNNorth Carolina State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In plants, RNA-directed DNA methylation (RdDM)-mediated transcriptional gene silencing (TGS) is a natural antiviral defense against geminiviruses. Several geminiviral proteins have been shown to target the enzymes related to the methyl cycle or histone modification; however, it remains largely unknown whether and by which mechanism geminiviruses directly inhibit RdDM-mediated TGS. In this study, we showed that

Indexed as

BegomovirusDNA MethylationDNA, ViralGeminiviridaeGene SilencingHost-Pathogen InteractionsNicotianaPlant DiseasesTranscription, GeneticViral ProteinsDNA, ViralViral ProteinsArgonaute 4CLCuMuVRdDM pathwayTGSV2

Identifiers

PMID30626668
PMCPMC6401443
OpenAlexW2911110535

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.