Evidence map›Paper›PMID 30626609›Full record

ArticleDiabetes2019

The Role of Prostaglandins in Disrupted Gastric Motor Activity Associated With Type 2 Diabetes.

Peter J Blair, Sung Jin Hwang, Matthew C Shonnard, Lauren E Peri, Yulia Bayguinov, Kenton M Sanders, Sean M Ward

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. CaCell calcium · 2021
    Article
  7. Experimental and therapeutic medicine · 2021
    Article
  8. Proteomics in gastroparesis: unique and overlapping protein signatures in diabetic and idiopathic gastroparesis.American journal of physiology. Gastrointestinal and liver physiology · 2019
    Article
  9. 15-Deoxy-∆-PPAR research · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Peter J BlairDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV.
Sung Jin HwangDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV.
Matthew C ShonnardDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV.
Lauren E PeriDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV.
Yulia BayguinovDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV.
Kenton M SandersDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV.
Sean M WardDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV smward@med.unr.edu.ORCID 0000-0003-0217-1535
University of Nevada, Reno · US

Funding

Tissue, Cell and Tissue Culture CoreP01DK041315 · NIDDK · UNIVERSITY OF NEVADA RENO · PI KEEF, KATHLEEN D · 1989 to 2018
$26.3M
Mechanisms underlying regional differences in gastric compliance in the stomach.R01DK057236 · NIDDK · UNIVERSITY OF NEVADA RENO · PI KENTON M SANDERS, Sean M Ward · 2000 to 2026
$7.1M
NIDDK NIH HHS P01 DK041315NIDDK NIH HHS R01 DK057236
6 · The paper itself

Abstract

Patients with diabetes often develop gastrointestinal motor problems, including gastroparesis. Previous studies have suggested this gastric motor disorder was a consequence of an enteric neuropathy. Disruptions in interstitial cells of Cajal (ICC) have also been reported. A thorough examination of functional changes in gastric motor activity during diabetes has not yet been performed. We comprehensively examined the gastric antrums of

Indexed as

AnimalsBlood GlucoseBlood Glucose Self-MonitoringCyclooxygenase 2Diabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2ElectrophysiologyHumansImmunohistochemistryMiceMice, Inbred C57BLMotor ActivityProstaglandinsReal-Time Polymerase Chain ReactionSignal TransductionBlood GlucoseCyclooxygenase 2Prostaglandins

Identifiers

PMID30626609
PMCPMC6385756
OpenAlexW2910862803

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.