ArticleJMIR research protocols2019
Association Between Residual Inhibition and Neural Activity in Patients with Tinnitus: Protocol for a Controlled Within- and Between-Subject Comparison Study.
Article in JMIR research protocols, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Linking brain activation to clinical outcomes: an fNIRS study in cochlear implant users and normal hearing individuals.Neurophotonics · 2026Article
- EEG spectral and microstate analysis originating residual inhibition of tinnitus induced by tailor-made notched music training.Frontiers in neuroscience · 2023Article
- Neural Activity During Audiovisual Speech Processing: Protocol For a Functional Neuroimaging Study.JMIR research protocols · 2022Article
- Prediction of Acoustic Residual Inhibition of Tinnitus Using a Brain-Inspired Spiking Neural Network Model.Brain sciences · 2021Article
- Susceptibility to Residual Inhibition Is Associated With Hearing Loss and Tinnitus Chronicity.Trends in hearingArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundElectroencephalography (EEG) studies indicate possible associations between tinnitus and changes in the neural activity. However, inconsistent results require further investigation to better understand such heterogeneity and inform the interpretation of previous findings.
objectiveThis study aims to investigate the feasibility of EEG measurements as an objective indicator for the identification of tinnitus-associated neural activities.
methodsTo reduce heterogeneity, participants served as their own control using residual inhibition (RI) to modulate the tinnitus perception in a within-subject EEG study design with a tinnitus group. In addition, comparison with a nontinnitus control group allowed for a between-subjects comparison. We will apply RI stimulation to generate tinnitus and nontinnitus conditions in the same subject. Furthermore, high-frequency audiometry (up to 13 kHz) and tinnitometry will be performed.
resultsThis work was funded by the Infrastructure Grant of the University of Bern, Bern, Switzerland and Bernafon AG, Bern, Switzerland. Enrollment for the study described in this protocol commenced in February 2018. Data analysis is currently under way and the first results are expected to be submitted for publication in 2019.
conclusionsThis study design helps in comparing the neural activity between conditions in the same individual, thereby addressing a notable limitation of previous EEG tinnitus studies. In addition, the high-frequency assessment will help to analyze and classify tinnitus symptoms beyond the conventional clinical standard. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR1-10.2196/12270.
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