Evidence map›Paper›PMID 30626437›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2019

Accelerated free-breathing 3D T1ρ cardiovascular magnetic resonance using multicoil compressed sensing.

Srikant Kamesh Iyer, Brianna Moon, Eileen Hwuang, Yuchi Han, Michael Solomon, Harold Litt, Walter R Witschey

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. 3D Whole-Heart Joint TNMR in biomedicine · 2026
    Article
  2. Simultaneous TMagnetic resonance in medicine · 2025
    Article
  3. 3D joint TMagnetic resonance in medicine · 2025
    Article
  4. Article
  5. European heart journal. Imaging methods and practice · 2025
    Article
  6. Article
  7. The future of cardiovascular magnetic resonance: All-in-one vs. real-time (Part 1).Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024
    Review
  8. Robust cardiacMagnetic resonance in medicine · 2023
    Article
  9. Article
  10. Magnetic resonance myocardial T1ρ mapping : Technical overview, challenges, emerging developments, and clinical applications.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Review
  11. SPICY: a method for single scan rotating frame relaxometry.Physical chemistry chemical physics : PCCP · 2023
    Article
  12. Quantification correction for free-breathing myocardial TJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Article
  13. Endogenous assessment of myocardial injury with single-shot model-based non-rigid motion-corrected T1 rho mapping.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  14. Performance Comparison of Compressed Sensing Algorithms for Accelerating TJournal of magnetic resonance imaging : JMRI · 2021
    Article
  15. Article
  16. Fast multicomponent 3D-TNMR in biomedicine · 2020
    Article
  17. Review
  18. Respiratory motion-compensated high-resolution 3D whole-heart T1ρ mapping.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Srikant Kamesh IyerDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Brianna MoonDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Eileen HwuangDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Yuchi HanDepartment of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Michael SolomonDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Harold LittDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Walter R WitscheyDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. witschey@pennmedicine.upenn.edu.
University of Pennsylvania · US

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
Multidisciplinary Training in Cardiovascular BiologyT32HL007954 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI DAVIES, PETER FRANCIS · 2000 to 2019
$9.9M
Training Program in Biomedical Imaging and Information SciencesT32EB009384 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI GEE, JAMES C, IVES, ZACHARY · 2009 to 2023
$4.0M
Cardiac MR imaging of hemorrhagic reperfusion injury after myocardial infarctionR01HL137984 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WITSCHEY, WALTER R.T. · 2018 to 2022
$2.8M
Nuclear Magnetic Tirho Relaxation in Acute and Chronic Myocardial InfarctionsR00HL108157 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WITSCHEY, WALTER R.T. · 2014 to 2016
$747k
NHLBI NIH HHS R00 HL108157NHLBI NIH HHS R01 HL137984NHLBI NIH HHS T32 HL007954NIBIB NIH HHS T32 EB009384NIH HHS UL1TR001878
6 · The paper itself

Abstract

backgroundEndogenous contrast T1ρ cardiovascular magnetic resonance (CMR) can detect scar or infiltrative fibrosis in patients with ischemic or non-ischemic cardiomyopathy. Existing 2D T1ρ techniques have limited spatial coverage or require multiple breath-holds. The purpose of this project was to develop an accelerated, free-breathing 3D T1ρ mapping sequence with whole left ventricle coverage using a multicoil, compressed sensing (CS) reconstruction technique for rapid reconstruction of undersampled k-space data.

methodsWe developed a cardiac- and respiratory-gated, free-breathing 3D T1ρ sequence and acquired data using a variable-density k-space sampling pattern (A = 3). The effect of the transient magnetization trajectory, incomplete recovery of magnetization between T1ρ-preparations (heart rate dependence), and k-space sampling pattern on T1ρ relaxation time error and edge blurring was analyzed using Bloch simulations for normal and chronically infarcted myocardium. Sequence accuracy and repeatability was evaluated using MnCl

resultsThe error in T1ρ due to incomplete recovery of magnetization between T1ρ-preparations was T1ρ

conclusionsThis is the first report of an accelerated, free-breathing 3D T1ρ mapping of the left ventricle. This technique may improve non-contrast myocardial tissue characterization in patients with heart disease in a scan time appropriate for patients.

Indexed as

Cardiac-Gated Imaging TechniquesFourier AnalysisRespiratory-Gated Imaging TechniquesCase-Control StudiesElectrocardiographyFeasibility StudiesHeart RateHumansMagnetic Resonance ImagingModels, CardiovascularMyocardial InfarctionMyocardiumPhantoms, ImagingPredictive Value of TestsReproducibility of ResultsRespirationCompressed sensingEndogenous contrast techniquesFast minimizationMulticoil reconstructionParametric mappingT1ρ

Identifiers

PMID30626437
PMCPMC6327532
OpenAlexW2911616354

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.