Evidence map›Paper›PMID 30626433›Full record

SynthesisSystematic reviews2019

Effectiveness of architectural separation of septic and aseptic operating theatres for improving process quality and patient outcomes: a systematic review.

Romy Scholz, Alexander Hönning, Julia Seifert, Nikolai Spranger, Dirk Stengel

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Systematic reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Romy ScholzCentre for Clinical Research, BG Hospital Unfallkrankenhaus Berlin, Berlin, Germany.
Alexander HönningCentre for Clinical Research, BG Hospital Unfallkrankenhaus Berlin, Berlin, Germany. alexander.hoenning@ukb.de.
Julia SeifertDepartment of Trauma and Orthopaedic Surgery, BG Hospital Unfallkrankenhaus Berlin, Berlin, Germany.
Nikolai SprangerDepartment of Trauma and Orthopaedic Surgery, BG Hospital Unfallkrankenhaus Berlin, Berlin, Germany.
Dirk StengelCentre for Clinical Research, BG Hospital Unfallkrankenhaus Berlin, Berlin, Germany.
Unfallkrankenhaus Berlin · DENational Association of Statutory Health Insurance Physicians · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArchitectural division of aseptic and septic operating theatres is a distinct structural feature of surgical departments in Germany. Internationally, hygienists and microbiologists mainly recommend functional separation (i.e. aseptic procedures first) without calling for separate operating floors and rooms. However, patients with severe musculoskeletal infections (e.g. joint empyema, spondylodiscitis, deep implant-associated infections) may benefit from the permanent availability of septic operating capacities without delay caused by an ongoing aseptic surgical program. A systematic literature review on the influence of a structural separation of septic and aseptic operating theatres on process and/or outcome quality has not yet been conducted.

methodsSystematic literature search in PubMed MEDLINE, Ovid Embase, CINAHL and the Cochrane Library, screening of referenced citations, and assessment of grey literature.

resultsA total of 572 articles were found through the systematic literature search. No head-to-head studies (neither randomised, quasi-randomised nor observational) were identified which examined the impact of structural separation of septic and aseptic operating theatres on process and/or outcome quality.

conclusionsThis review did not identify evidence in favour nor against architectural separation of septic or aseptic operating theatre. Specifically, there is no evidence of a harmful effect of architectural separation. Unless prospective studies, ideally randomised trials, will be available, it is unjustified to call for abolishing established hospital structures. Future investigations must address patient-centered endpoints, surgical site infections, process quality and hospital economy. SYSTEMATIC REVIEW REGISTRATION: PROSPERO (International prospective register of systematic reviews): CRD42018086568.

Indexed as

AsepsisDrug Resistance, MultipleHospital Design and ConstructionInfection ControlOperating RoomsOutcome and Process Assessment, Health CareCross InfectionEquipment ContaminationGermanyHumansProsthesis-Related InfectionsQuality ImprovementTime FactorsWound HealingAsepticOperating roomProcess qualitySepticSpatial separationSurgical site infection

Identifiers

PMID30626433
PMCPMC6325836
OpenAlexW2910725906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.