ArticleBMC nephrology2019
IHDIP: a controlled randomized trial to assess the security and effectiveness of the incremental hemodialysis in incident patients.
Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03239808 (Assessment of the Incremental Haemodialysis Security and Effectiveness in Incident Patients), which is not on this map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of the Incremental Haemodialysis Security and Effectiveness in Incident Patients
Who cites it
21 citing papers in PubMed, 43 citations in OpenAlex.
- Ten tips for the first hemodialysis sessions.Clinical kidney journal · 2026Review
- Perspectives on Quality of Life, Vascular Access, and Fluid Balance in Incremental Hemodialysis: A Narrative Review.Kidney360 · 2026Review
- Incremental vs. standard hemodialysis for preserving residual kidney function: a case-control study.BMC nephrology · 2025Observational
- Clinical challenges and individualized approaches to dialysis therapy in older adults.The Korean journal of internal medicine · 2025Review
- Nutritional Ultrasound in the Morphofunctional Assessment of Malnutrition in Patients Undergoing Incremental Versus Conventional Hemodialysis: A Comparative Study.Medicina (Kaunas, Lithuania) · 2025Observational
- Reduced intensity incremental hemodialysis start does not decrease life expectancy and saves money: results of the RIDDLE study.Journal of nephrology · 2025Article
- Incremental hemodialysis and vascular access complications: a 12-year experience in a hospital hemodialysis unit.Journal of nephrology · 2024Article
- A practical approach to implementing incremental haemodialysis.Journal of nephrology · 2024Review
- Incremental dialysis: two complementary views.Clinical kidney journal · 2024Article
- Efficacy and Safety of the Use of SGLT2 Inhibitors in Patients on Incremental Hemodialysis: Maximizing Residual Renal Function, Is There a Role for SGLT2 Inhibitors?Biomedicines · 2023Article
- Does delivering more dialysis improve clinical outcomes? What randomized controlled trials have shown.Journal of nephrology · 2022Review
- Routine assessment of kidney urea clearance, dialysis dose and protein catabolic rate in the once-weekly haemodialysis regimen.Journal of nephrology · 2021Article
- Improving the "second generation Daugirdas equation" to estimate Kt/V on the once-weekly haemodialysis schedule.Journal of nephrology · 2021Article
- Article
- The cardiovascular-dialysis nexus: the transition to dialysis is a treacherous time for the heart.European heart journal · 2021Review
- Knowledge and Practice of Incremental Hemodialysis: A Survey of Canadian Nephrologists.Canadian journal of kidney health and disease · 2021Article
- Article
- Narrative Review of Incremental Hemodialysis.Kidney international reports · 2020Review
- Incremental hemodialysis, a valuable option for the frail elderly patient.Journal of nephrology · 2019Review
- Patiromer in a Patient with Severe Hyperkalemia on Incremental Hemodialysis with 1 Session per Week: A Case Report and Literature Review.Case reports in nephrology and dialysisArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 15 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMost people who make the transition to renal replacement therapy (RRT) are treated with a fixed dose thrice-weekly hemodialysis réegimen, without considering their residual kidney function (RKF). Recent papers inform us that incremental hemodialysis is associated with preservation of RKF, whenever compared with conventional hemodialysis. The objective of the present controlled randomized trial (RCT) is to determine if start HD with one sessions per week (1-Wk/HD), it is associated with better patient survival and other safety parameters. METHODS/
designIHDIP is a multicenter RCT experimental open trial. It is randomized in a 1:1 ratio and controlled through usual clinical practice, with a low intervention level and non-commercial. It includes 152 incident patients older than 18 years, with a RRF of ≥4 ml/min/1.73 m2, measured by renal clearance of urea (KrU). The intervention group includes 76 patients who will start with incremental HD (1-Wk/HD). The control group includes 76 patients who will start with thrice-weekly hemodialysis régimen. The primary outcome is assessing the survival rate, while the secondary outcomes are the morbidity rate, the clinical parameters, the quality of life and the efficiency. DISCUSSION: This study will enable to know the number of sessions a patient should receive when starting HD, depending on his RRF. The potentially important clinical and financial implications of incremental hemodialysis warrant this RCT.
trial registrationU.S. National Institutes of Health, ClinicalTrials.gov . Number: NCT03239808 , completed 13/04/2017. SPONSOR: Foundation for Training and Research of Health Professionals of Extremadura.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.