Evidence map›Paper›PMID 30626117›Full record

ReviewNutrients2019

Role of Dietary Lipids in Modulating Inflammation through the Gut Microbiota.

Paul J Wisniewski, Robert A Dowden, Sara C Campbell

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Paul J WisniewskiDepartment of Kinesiology and Health and The Rutgers Center for Lipid Research and The Center for Digestive Health, New Jersey Institute for Food, Nutrition and Health, Rutgers University, New Brunswick, NJ 08901, USA. paulw@kines.rutgers.edu.
Robert A DowdenDepartment of Kinesiology and Health and The Rutgers Center for Lipid Research and The Center for Digestive Health, New Jersey Institute for Food, Nutrition and Health, Rutgers University, New Brunswick, NJ 08901, USA. rad267@rutgers.edu.
Sara C CampbellDepartment of Kinesiology and Health and The Rutgers Center for Lipid Research and The Center for Digestive Health, New Jersey Institute for Food, Nutrition and Health, Rutgers University, New Brunswick, NJ 08901, USA. saracamp@kines.rutgers.edu.
Rutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation and its resolution is a tenuous balance that is under constant contest. Though several regulatory mechanisms are employed to maintain homeostasis, disruptions in the regulation of inflammation can lead to detrimental effects for the host. Of note, the gut and microbial dysbiosis are implicated in the pathology of systemic chronic low-grade inflammation which has been linked to several metabolic diseases. What remains to be described is the extent to which dietary fat and concomitant changes in the gut microbiota contribute to, or arise from, the onset of metabolic disorders. The present review will highlight the role of microorganisms in host energy regulation and several mechanisms that contribute to inflammatory pathways. This review will also discuss the immunomodulatory effects of the endocannabinoid system and its link with the gut microbiota. Finally, a brief discussion arguing for improved taxonomic resolution (at the species and strain level) is needed to deepen our current knowledge of the microbiota and host inflammatory state.

Indexed as

DietDysbiosisAnimalsDietary FatsEndocannabinoidsGastrointestinal MicrobiomeGastrointestinal TractHumansInflammationMetabolic DiseasesSpecies SpecificityDietary FatsEndocannabinoidsdybiosisgutgut permeabilitylipidsLPSmicrobiotaobesity

Identifiers

PMID30626117
PMCPMC6357048
OpenAlexW2910846700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.