Evidence map›Paper›PMID 30626083›Full record

ArticleJournal of fungi (Basel, Switzerland)2019

In Vitro and In Vivo Evaluation of Voriconazole-Containing Antifungal Combinations against Mucorales Using a

Daiana Macedo, Florencia Leonardelli, Catiana Dudiuk, Roxana G Vitale, Eleodoro Del Valle, Gustavo Giusiano, Soledad Gamarra, Guillermo Garcia-Effron

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Journal of fungi (Basel, Switzerland) · 2025
    Review
  4. AlternativeFrontiers in cellular and infection microbiology · 2024
    Review
  5. Miltefosine: A Repurposing Drug against Mucorales Pathogens.Journal of fungi (Basel, Switzerland) · 2023
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Microorganisms · 2020
    Review
  12. Special Issue: Mucorales and Mucormycosis.Journal of fungi (Basel, Switzerland) · 2019
    Article
  13. Animal Models to Study Mucormycosis.Journal of fungi (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Daiana MacedoConsejo Nacional de Investigaciones Científicas y Tecnológicas CONICET, Laboratorio de Micología y Diagnóstico Molecular-Cátedra de Parasitología y Micología-Facultad de Bioquímica y Ciencias Biológicas-Universidad Nacional del Litoral, Santa Fe CP 3000, Argentina. daiana.magalimacedo@gmail.com.
Florencia LeonardelliConsejo Nacional de Investigaciones Científicas y Tecnológicas CONICET, Laboratorio de Micología y Diagnóstico Molecular-Cátedra de Parasitología y Micología-Facultad de Bioquímica y Ciencias Biológicas-Universidad Nacional del Litoral, Santa Fe CP 3000, Argentina. leonardellifs@gmail.com.
Catiana DudiukConsejo Nacional de Investigaciones Científicas y Tecnológicas CONICET, Laboratorio de Micología y Diagnóstico Molecular-Cátedra de Parasitología y Micología-Facultad de Bioquímica y Ciencias Biológicas-Universidad Nacional del Litoral, Santa Fe CP 3000, Argentina. cbdudiuk@gmail.com.
Roxana G VitaleUnidad de Parasitología, Laboratorio de Micología, Hospital Ramos Mejía, CONICET, Ciudad Autónoma de Buenos Aires CP1221, Argentina. Roxana_vitale@yahoo.com.
Eleodoro Del ValleFacultad de Ciencias Agrarias, Universidad Nacional del Litoral, Esperanza CP3080, Argentina. eleodoro77@gmail.com.
Gustavo GiusianoConsejo Nacional de Investigaciones Científicas y Tecnológicas CONICET, Área Micología, Instituto de Medicina Regional, Universidad Nacional del Nordeste, Resistencia CP3500, Argentina. gustavogiusiano@yahoo.com.ar.ORCID 0000-0003-4696-4158
Soledad GamarraLaboratorio de Micología y Diagnóstico Molecular-Cátedra de Parasitología y Micología-Facultad de Bioquímica y Ciencias Biológicas-Universidad Nacional del Litoral, Santa Fe CP3000, Argentina. mgamarra@fbcb.unl.edu.ar.
Guillermo Garcia-EffronConsejo Nacional de Investigaciones Científicas y Tecnológicas CONICET, Laboratorio de Micología y Diagnóstico Molecular-Cátedra de Parasitología y Micología-Facultad de Bioquímica y Ciencias Biológicas-Universidad Nacional del Litoral, Santa Fe CP 3000, Argentina. ggarcia@unl.edu.ar.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidad Nacional del Litoral · AR

Funding

Ministerio de Ciencia, Tecnología e Innovación Productiva PICT 2013-1985
6 · The paper itself

Abstract

Mucorales are resistant to most antifungals. Mucormycosis associated mortality is unacceptable and new treatment approaches are needed. The objectives of this work were (i) to evaluate the nature and intensity of the in vitro effect of three drugs combinations which included voriconazole (plus amphotericin B, posaconazole and caspofungin) against 25 strains of six different Mucorales species; (ii) to evaluate a

Indexed as

amphotericin BazoleGalleria mellonellamucormycosissynergismvoriconazole

Identifiers

PMID30626083
PMCPMC6462937
OpenAlexW2909626957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.