ArticleMembranes2019
Preparation and Properties of Carboxymethyl Chitosan/Alginate/Tranexamic Acid Composite Films.
Article in Membranes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Article
- Application of multilayer drug-loaded hydrogels in protection of open abdomen wounds.RSC advances · 2026Article
- Implantation of nano-MOFs into chitosan/sodium alginate hydrogels: boosting the electroanalytical response of chlorogenic acid in food samples.RSC advances · 2025Article
- Chitosan and Its Derivatives: Preparation and Antibacterial Properties.Materials (Basel, Switzerland) · 2023Review
- Mesenchymal stem cells encapsulation in chitosan and carboxymethyl chitosan hydrogels to enhance osteo-differentiation.Molecular biology reports · 2022Article
- Hemostatic Alginate/Nano-Hydroxyapatite Composite Aerogel Loaded with Tranexamic Acid for the Potential Protection against Alveolar Osteitis.Pharmaceutics · 2022Article
- Fungal Chitosan-Derived Biomaterials Modified withPolymers · 2021Article
- Application and outlook of topical hemostatic materials: a narrative review.Annals of translational medicine · 2021Review
- Quality by Design Approach for Preparation of Zolmitriptan/Chitosan Nanostructured Lipid Carrier Particles - Formulation and Pharmacodynamic Assessment.International journal of nanomedicine · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
In this study, the porous composite films of carboxymethyl chitosan/alginate/tranexamic acid were fabricated, with calcium chloride as the crosslinking agent and glycerin as a plasticizer. The composite films were characterized by scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. The properties of the composite films, including water absorption, air permeability, and cumulative release rate, were tested. In addition, their hemostatic performance was evaluated. The results showed that the appearance of the films with good adhesion was smooth and porous. FTIR showed that chemical crosslinking between carboxymethyl chitosan and sodium alginate was successful. The excellent cumulative release of tranexamic acid in the composite films (60⁻80%) gives the films a significant procoagulant effect. This has good prospects for the development of medical hemostasis materials.
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Registered trials
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