Evidence map›Paper›PMID 30626014›Full record

ArticleInternational journal of molecular sciences2019

Proteomic Signatures Reveal Differences in Stress Response, Antioxidant Defense and Proteasomal Activity in Fertile Men with High Seminal ROS Levels.

Tânia R Dias, Luna Samanta, Ashok Agarwal, Peter N Pushparaj, Manesh Kumar Panner Selvam, Rakesh Sharma

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 42 citations in OpenAlex.

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  11. Influence of Risk Factors for Male Infertility on Sperm Protein Composition.International journal of molecular sciences · 2021
    Review
  12. Review
  13. Article
  14. Seminal Plasma Proteomic Biomarkers of Oxidative Stress.International journal of molecular sciences · 2020
    Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 3 countries.

Tânia R DiasAmerican Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH 44195, USA. taniadias89@gmail.com.ORCID 0000-0002-2336-8006
Luna SamantaAmerican Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH 44195, USA. lsamanta@ravenshawuniversity.ac.in.ORCID 0000-0002-2969-0071
Ashok AgarwalAmerican Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH 44195, USA. agarwaa@ccf.org.ORCID 0000-0003-0585-1026
Peter N PushparajCenter of Excellence in Genomic Medicine Research, Jeddah 21589, Saudi Arabia. peter.n.pushparaj@gmail.com.ORCID 0000-0001-7574-1880
Manesh Kumar Panner SelvamAmerican Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH 44195, USA. manesh.balu@gmail.com.
Rakesh SharmaAmerican Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH 44195, USA. sharmar@ccf.org.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elevated levels of reactive oxygen species (ROS) are a major cause of male infertility. However, some men with high seminal ROS levels are still fertile. The main objective of this study was to understand the molecular mechanism(s) responsible for the preservation of fertility in those men. Semen samples from fertile men were divided into two groups: control (

Indexed as

Oxidative StressAntioxidantsFertilityHumansMaleMolecular Sequence AnnotationProteomicsReactive Oxygen SpeciesSemenSpermatozoaAntioxidantsReactive Oxygen Speciesantioxidantsbioinformaticschemiluminescencedifferentially expressed proteinsproteomicsreactive oxygen speciesseminal plasmaspermatozoaWestern blot

Identifiers

PMID30626014
PMCPMC6337289
OpenAlexW2910591761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.