Evidence map›Paper›PMID 30625349›Full record

ReviewNeuroscience letters2019

A decade of diverse microglial-neuronal physical interactions in the brain (2008-2018).

Joseph O Uweru, Ukpong B Eyo

Open access · greenAbstract readReview
In one paragraph

Review in Neuroscience letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Association between APOE genotype and microglial cell morphology.Journal of neuropathology and experimental neurology · 2023
    Article
  6. Review
  7. A Comparative Biology of Microglia Across Species.Frontiers in cell and developmental biology · 2021
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Joseph O UweruDepartment of Neuroscience, University of Virginia, Charlottesville, VA, United States; Neuroscience Graduate Program, University of Virginia, Charlottesville, VA, United States; Center for Brain Immunology and Glia (BIG), University of Virginia, Charlottesville, VA, United States.
Ukpong B EyoDepartment of Neuroscience, University of Virginia, Charlottesville, VA, United States; Neuroscience Graduate Program, University of Virginia, Charlottesville, VA, United States; Center for Brain Immunology and Glia (BIG), University of Virginia, Charlottesville, VA, United States. Electronic address: ube9q@virginia.edu.
University of Virginia · US

Funding

Microglial P2Y12 Receptors in Normal Developmental Physiology and SeizuresK22NS104392 · NINDS · UNIVERSITY OF VIRGINIA · PI EYO, UKPONG BASSEY · 2017 to 2020
$813k
NINDS NIH HHS K22 NS104392
6 · The paper itself

Abstract

Microglia are unique cells of the central nervous system (CNS) with a distinct ontogeny and molecular profile. They are the predominant immune resident cell in the CNS. Recent studies have revealed a diversity of transient and terminal physical interactions between microglia and neurons in the vertebrate brain. In this review, we follow the historical trail of the discovery of these interactions, summarize their notable features, provide implications of these discoveries to CNS function, emphasize emerging themes along the way and peak into the future of what outstanding questions remain to move the field forward.

Indexed as

AnimalsAxonsBrainDendritesHumansMicrogliaNeuronsPhagocytosisSynapsesMicrogliaNeuronsNMDARP2Y12Physical interactionsTwo photon imaging

Identifiers

PMID30625349
PMCPMC6435396
OpenAlexW2907864972

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.