ArticleCell metabolism2019
β Cell Dysfunction in Type 2 Diabetes: Drained of Energy?
Article in Cell metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 44 citations in OpenAlex.
- The effects of early short-term insulin treatment vs. glimepiride on beta cell function in newly diagnosed type 2 diabetes with HbA1c above 9.Turkish journal of medical sciences · 2023Trial
- Perturbations in beta-cell heterogeneity in the pathogenesis of type 2 diabetes.Nature cell biology · 2023Article
- A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes.Nature cell biology · 2023Article
- Prolonged activation of NMDA receptors induces dedifferentiation of islet β cells in mice.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022Article
- Phosphoserine phosphatase as a prognostic biomarker in patients with gastric cancer and its potential association with immune cells.BMC gastroenterology · 2022Article
- Phosphoserine phosphatase as an indicator for survival through potentially influencing the infiltration levels of immune cells in neuroblastoma.Frontiers in cell and developmental biology · 2022Article
- Endocrine role of bone in the regulation of energy metabolism.Bone research · 2021Review
- Nanoscale Amperometry Reveals that Only a Fraction of Vesicular Serotonin Content is Released During Exocytosis from Beta Cells.Angewandte Chemie (International ed. in English) · 2021Article
- Identification of key candidate genes and pathways revealing the protective effect of liraglutide on diabetic cardiac muscle by integrated bioinformatics analysis.Annals of translational medicine · 2020Article
- Aged-senescent cells contribute to impaired heart regeneration.Aging cell · 2019Article
- Ameliorative Effect and Mechanism of the Purified Anthraquinone-Glycoside Preparation fromMolecules (Basel, Switzerland) · 2019Article
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Type 2 diabetes is a progressive disorder, but exactly how the progression occurs remains unknown. In this issue of Cell Metabolism, Zhang et al. (2019) present evidence that diabetes, via hyperglycemia, leads to aberrant insertion of a mitochondrial ion channel in the plasma membrane, rendering it leaky to key intracellular signaling molecules with resultant suppression of insulin secretion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.