ArticleAmerican journal of hypertension2019
Maternal Gestational Diabetes Is Associated With Offspring's Hypertension.
Article in American journal of hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Gestational diabetes mellitus and development of intergenerational overall and subtypes of cardiovascular diseases: a systematic review and meta-analysis.Cardiovascular diabetology · 2024Pooled it
- The therapeutic effects of attending a one-day outpatient service on patients with gestational diabetes and different pre-pregnancy body mass indices.Frontiers in public health · 2022Trial
- Higher maternal weight is related to poorer fetal autonomic function.Journal of developmental origins of health and disease · 2021Trial
- Cod-Liver Oil Improves Metabolic Indices and hs-CRP Levels in Gestational Diabetes Mellitus Patients: A Double-Blind Randomized Controlled Trial.Journal of diabetes research · 2019Trial
- Dietary macronutrient substitutions and cardiometabolic outcomes in children with and without gestational diabetes exposure: a cross-sectional analysis.The American journal of clinical nutrition · 2026Article
- Subclinical Changes in Cardiovascular Function During the Neonatal Period in Infants Born to Mothers With Diabetes.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- Prenatal factors shaping adolescent cardiovascular function and cardiometabolic risk trajectories.Frontiers in pediatrics · 2026Review
- The Adverse Influence of Maternal Glycaemia During Pregnancy on Offspring's Cardiometabolic Health Profiles.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Omentin-1 protects against endothelial dysfunction through the AMPK/KLF2/eNOS pathway in adult rat offspring exposed to maternal diabetes.Nutrition & diabetes · 2025Article
- GDM enhanced acetylcholine induced vasoconstriction in human umbilical vein via CHRM3 and CACNA1C upregulation linked to promoter hypomethylation.Scientific reports · 2025Article
- Influence of gestational diabetes mellitus on the cardiovascular system and its underlying mechanisms.Frontiers in endocrinology · 2025Review
- Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy cohort.Frontiers in nutrition · 2025Article
- Crosstalk between hypertension and diabetes: focusing on pregnancy and offspring. A systematic review.Frontiers in physiology · 2025Review
- Impact of Maternal Hyperglycemic and Hypertensive Disorders on Perinatal Outcomes Across the COVID-19 Pandemic.Women's health reports (New Rochelle, N.Y.) · 2025Article
- Kidney Programming and Hypertension: Linking Prenatal Development to Adulthood.International journal of molecular sciences · 2024Review
- Impacts of low birthweight on kidney development and intergenerational growth of the offspring.iScience · 2024Article
- Trends in the Incidence of Gestational Diabetes Mellitus Among the Medicaid Population Before and During the COVID-19 Pandemic.Journal of women's health (2002) · 2024Article
- Recent Findings on Exercise Therapy for Blood Glucose Management in Patients with Gestational Diabetes.Journal of clinical medicine · 2024Review
- Motivational factors for dietary intake behavior in gestational diabetes mellitus: A cross-sectional study.Heliyon · 2024Article
- Inflammation and Oxidative Stress Induced by Obesity, Gestational Diabetes, and Preeclampsia in Pregnancy: Role of High-Density Lipoproteins as Vectors for Bioactive Compounds.Antioxidants (Basel, Switzerland) · 2023Review
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Authors and funding
14 authors at 7 institutions in 4 countries.
Funding
Abstract
objectiveSeveral studies assessed maternal gestational diabetes mellitus (GDM) with the risk of childhood high blood pressure, and the results were inconsistent. We investigated the association between maternal GDM and hypertension risk in offspring during early childhood.
methodsWe performed a large study in 1,156 mother-child pairs (578 GDM and 578 non-GDM matched by their offspring's age and sex). Maternal GDM was diagnosed according to the World Health Organization criteria. Childhood height, weight, and blood pressure were measured using standardized methods. Age-, sex-, and height-specific blood pressure Z score, childhood hypertension, and high blood pressure were evaluated according to the reference range of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents.
resultsAfter adjustment for maternal and children's characteristics, children born to mothers with GDM during pregnancy had higher mean values of systolic blood pressure Z score (0.09 vs. -0.17), and higher prevalence of hypertension (6.4% vs. 3.5%) and high blood pressure (15.6% vs. 9.3%) in comparison with their counterparts born to mothers without GDM during pregnancy (all P values <0.05). Multivariable-adjusted odds ratios among children of mothers with GDM compared with children of mothers without GDM were 2.32 (95% confidence intervals [CI] 1.16-4.62) for hypertension and 1.89 (95% CI 1.24-2.86) for high blood pressure, respectively.
conclusionsMaternal GDM was associated with an increased risk of hypertension in the offspring. Controlling maternal GDM may be important for preventing childhood hypertension in the affected offspring.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.