Evidence map›Paper›PMID 30624351›Full record

ArticleHealth physics2019

A Dosimetry Study of Portable X-ray Fluorescence in Vivo Metal Measurements.

Aaron J Specht, Xinxin Zhang, Benjamin D Goodman, Ed Maher, Marc G Weisskopf, Linda H Nie

Open access · greenAbstract read
In one paragraph

Article in Health physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Ways to Measure Metals: From ICP-MS to XRF.Current environmental health reports · 2025
    Review
  4. Review
  5. Article
  6. In vivo quantification of strontium in bone among adults using portable x-ray fluorescence.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Aaron J SpechtHarvard T.H. Chan School of Public Health Boston, MA.
Xinxin ZhangSchool of Health Sciences, Purdue University West Lafayette, IN.
Benjamin D GoodmanSaint Francis Medical Center, Cape Girardeau, MO.
Ed MaherHarvard T.H. Chan School of Public Health Boston, MA.
Marc G WeisskopfHarvard T.H. Chan School of Public Health Boston, MA.
Linda H NieSchool of Health Sciences, Purdue University West Lafayette, IN.
Harvard University · USPurdue University West Lafayette · USSaint Francis Medical Center · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
University of Michigan ERC-supplement (TRT)T42OH008455 · OH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NEITZEL, RICHARD L · 2005 to 2025
$32.3M
Early and late-life metal exposures and Alzheimer's diseaseR01ES024165 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI WEISSKOPF, MARC G · 2014 to 2019
$3.3M
Validation of Portable XRF for In Vivo Measurement of Heavy Metal ExposuresR21ES024700 · NIEHS · RUSH UNIVERSITY MEDICAL CENTER · PI NIE, LINDA H, WEISSKOPF, MARC G · 2015 to 2018
$712k
NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES024165NIEHS NIH HHS R21 ES024700NIOSH CDC HHS T42 OH008455
6 · The paper itself

Abstract

Portable x-ray fluorescence devices have grown in popularity for possible metal exposure assessment using in vivo measurements of bone and toenail. These measurements are accompanied by a small radiation dose, which is typically assessed by radiation safety committees to be minimal. However, an understanding of precise dose under different instrument conditions is still needed. This study set out to do a thorough investigation of the exact dose measurements using optically stimulated dosimeters, thermoluminescent dosimeters, and simulation with a Monte Carlo N-Particle transport code to assess the skin and total-body effective dose typical of portable x-ray fluorescence devices. We showed normal linear relationships between measurement time, x-ray tube current, and radiation dose with the device, and we showed a second order polynomial relationship with increasing voltage and radiation dose. Dose was quantified using thermoluminescent dosimeters, optically stimulated dosimeters, and simulations, which gave similar dose estimations. Skin dose for a standard 50-kV, 40-μA measurement for bone and toenail in vivo was 48.5 and 28.7 mSv, respectively, according to simulation results. Total-body effective dose was shown as 3.4 and 2.0 μSv for in vivo bone and toenail measurements, respectively, for adults using the portable x-ray fluorescence device.

Indexed as

FluorescencePhantoms, ImagingAdultBone and BonesChildChild, PreschoolFemaleHumansMaleMetalsMonte Carlo MethodNailsRadiation DosageRadiometrySkinThermoluminescent DosimetryMetals

Identifiers

PMID30624351
PMCPMC6433501
OpenAlexW2909135440

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.