Evidence map›Paper›PMID 30623727›Full record

ArticleAmerican journal of physiology. Renal physiology2019

Kir4.1/Kir5.1 in the DCT plays a role in the regulation of renal K

Xiao-Tong Su, David H Ellison, Wen-Hui Wang

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
  2. Mechanistic target of rapamycin complex-1 plays a role in inhibiting kidney KAmerican journal of physiology. Renal physiology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Deletion of KS-WNK1 promotes NCC activation by increasing WNK1/4 abundance.American journal of physiology. Renal physiology · 2024
    Article
  8. Article
  9. Role of calcineurin in regulating renal potassium (KActa physiologica (Oxford, England) · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Thirty years of the NaCl cotransporter: from cloning to physiology and structure.American journal of physiology. Renal physiology · 2023
    Review
  16. Article
  17. Article
  18. Control of sodium and potassium homeostasis by renal distal convoluted tubules.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Xiao-Tong SuDepartment of Pharmacology, New York Medical College, Valhalla, New York.
David H EllisonDivision of Nephrology and Hypertension, School of Medicine, Oregon Health and Science University , Portland, Oregon.ORCID 0000-0003-2915-265X
Wen-Hui WangDepartment of Pharmacology, New York Medical College, Valhalla, New York.
New York Medical College · USOregon Health & Science University · US

Funding

WNK Kinase Regulation of Thiazide-sensitive NaCl TransportR01DK051496 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI David Hoadley Ellison, CHAO-LING YANG · 1998 to 2026
$8.4M
Role of Kir4.1 in Regulating NCC and ROMK in DCTR01DK054983 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID H, WANG, WENHUI · 2001 to 2020
$7.4M
Renal Effects of AldosteroneI01BX002228 · VA · PORTLAND VA MEDICAL CENTER · PI ELLISON, DAVID H · 2014 to 2021
–
BLRD VA I01 BX002228NIDDK NIH HHS R01 DK051496NIDDK NIH HHS R01 DK054983
6 · The paper itself

Abstract

The aim of this mini review is to provide an overview regarding the role of inwardly rectifying potassium channel 4.1 (Kir4.1)/Kir5.1 in regulating renal K

Indexed as

AnimalsBiological TransportHumansKcnj10 ChannelKidney Tubules, DistalKir5.1 ChannelPotassiumPotassium Channels, Inwardly RectifyingSolute Carrier Family 12, Member 1Solute Carrier Family 12, Member 3Kcnj10 ChannelKir5.1 ChannelPotassiumPotassium Channels, Inwardly RectifyingSolute Carrier Family 12, Member 1Solute Carrier Family 12, Member 3distal convoluted tubuleK excretionNCCNKCC2

Identifiers

PMID30623727
PMCPMC6459306
OpenAlexW2908807938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.