Evidence map›Paper›PMID 30623643›Full record

ArticleACS infectious diseases2019

Generation of

Clayton Evert, Tina Loesekann, Ganapati Bhat, Asif Shajahan, Roberto Sonon, Parastoo Azadi, Ryan C Hunter

Abstract readEvaluation Study
In one paragraph

Article in ACS infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Clayton EvertDepartment of Microbiology & Immunology , University of Minnesota , 689 23rd Avenue SE , Minneapolis , Minnesota 55455 , United States.
Tina LoesekannDepartment of Microbiology & Immunology , University of Minnesota , 689 23rd Avenue SE , Minneapolis , Minnesota 55455 , United States.
Ganapati BhatComplex Carbohydrate Research Center , University of Georgia , 315 Riverbend Road , Athens , Georgia 30602 , United States.
Asif ShajahanComplex Carbohydrate Research Center , University of Georgia , 315 Riverbend Road , Athens , Georgia 30602 , United States.ORCID 0000-0002-4804-1130
Roberto SononComplex Carbohydrate Research Center , University of Georgia , 315 Riverbend Road , Athens , Georgia 30602 , United States.
Parastoo AzadiComplex Carbohydrate Research Center , University of Georgia , 315 Riverbend Road , Athens , Georgia 30602 , United States.
Ryan C HunterDepartment of Microbiology & Immunology , University of Minnesota , 689 23rd Avenue SE , Minneapolis , Minnesota 55455 , United States.ORCID 0000-0003-3841-1676

Funding

Bacterial mucin degradation in cystic fibrosis airway disease.R01HL136919 · NHLBI · UNIVERSITY OF MINNESOTA · PI HUNTER, RYAN COULSON · 2017 to 2021
$2.1M
Orbitrap Fusion Tribrid Mass SpectrometerS10OD018530 · OD · UNIVERSITY OF GEORGIA · PI AZADI, PARASTOO · 2014 to 2014
$750k
NHLBI NIH HHS R01 HL136919NIH HHS S10 OD018530
6 · The paper itself

Abstract

Stable isotope probing (SIP) has emerged as a powerful tool to address key questions about microbiota structure and function. To date, diverse isotopically labeled substrates have been used to characterize in situ growth activity of specific bacterial taxa and have revealed the flux of bioavailable substrates through microbial communities associated with health and disease. A major limitation to the growth of the field is the dearth of biologically relevant "heavy" labeled substrates. Mucin glycoproteins, for example, comprise an abundant source of carbon in the gut, oral cavity, respiratory tract, and other mucosal surfaces but are not commercially available. Here, we describe a method to incorporate a

Indexed as

Gastrointestinal MicrobiomeAnimalsBacteriaCarbon IsotopesGastrointestinal TractGlucoseHumansIsotope LabelingMicrobiotaMucin 5ACOligosaccharidesCarbon IsotopesGlucoseMUC5AC protein, humanMucin 5ACOligosaccharidesCalu-3microbial ecologyMUC5ACmucinstable isotope probing

Identifiers

PMID30623643
PMCPMC6613647

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.