ArticleEuropean journal of epidemiology2019
The risk of breast and gynecological cancer in women with a diagnosis of infertility: a nationwide population-based study.
Article in European journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Ovulation induction drug and ovarian cancer: an updated systematic review and meta-analysis.Journal of ovarian research · 2023Pooled it
- The association between endometriosis and risk of endometrial cancer and breast cancer: a meta-analysis.BMC women's health · 2022Pooled it
- No association between abortion and risk of breast cancer among nulliparous women: Evidence from a meta-analysis.Medicine · 2020Pooled it
- PCOS and breast cancer risk: hormonal modulation and epidemiological trends.Reproductive health · 2026Review
- Endometriosis and Endometrial Cancer-Association Between Biological Mechanisms and Its Clinical Implications.Journal of clinical medicine · 2026Review
- Magnetic resonance imaging patterns of premenopausal gynaecological conditions among women at Muhimbili National Hospital.PloS one · 2026Article
- Trends in the Incidence of Ovarian Cancer Among Premenopausal and Postmenopausal Women in the United States, 2001 to 2021.Cancers · 2025Article
- Correlation between Castelli risk index-I and female infertility: A cross-sectional study.Lipids in health and disease · 2025Article
- Mechanism of Cnidii Fructus in the Treatment of Infertility Based on Network Pharmacology and Molecular Docking Analysis Technology.Biochemical genetics · 2025Article
- Association between gynecological cancers and female infertility: insights from bidirectional Mendelian randomization analysis.BMC women's health · 2025Article
- Breast and Ovarian Cancers' Incidence Trends Among Iraqi Women During 2012-2022 and Their Relationship to Fertility Patterns.Sultan Qaboos University medical journal · 2025Article
- Treatment outcomes and the associated factors among breast cancer patients in Tanzania: a retrospective cohort study.Ecancermedicalscience · 2025Article
- Preliminary comparison of net gain in final adult height of girls with early menarche treated with or without gonadotropin-releasing hormone agonist.Translational pediatrics · 2024Article
- Infertility treatments and risk of breast benign diseases: a case‒control study.BMC women's health · 2024Article
- Unraveling the Role ofPakistan journal of medical sciences · 2024Article
- Infertility and risk of postmenopausal breast cancer in the women's health initiative.Breast cancer research and treatment · 2024Article
- Effects of physical activity on infertility in reproductive females.Reproductive biology and endocrinology : RB&E · 2024Article
- Genetically identification of endometriosis and cancers risk in women through a two-sample Mendelian randomization study.Scientific reports · 2024Article
- Gynecological Cancers and Microbiota Dynamics: Insights into Pathogenesis and Therapy.International journal of molecular sciences · 2024Review
- Decoding connections in the European population: serum uric acid, sex hormone-binding globulin, total testosterone, estradiol, and female infertility - advanced bidirectional and mediative Mendelian randomization.Frontiers in endocrinology · 2024Article
Corrections and comments
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5 authors.
Funding
Abstract
Some studies have suggested that infertility is a risk factor for endometrial, ovarian and breast cancer. The study aimed to create a comprehensive picture of the association between infertility and the risk of ovarian, endometrial and breast cancer, and whether any association could be explained by ovulatory disturbances, endometriosis or nulliparity. In a population-based cohort of 2,882,847 women, cox regression analysis was used to investigate cancer incidence among infertile women. Overall, infertility was associated with a higher incidence rate of ovarian (adjusted hazard ratio [aHR] 1.53, 95% confidence interval [CI] 1.38-1.71) and endometrial cancer (aHR 1.25, 95% CI 1.11-1.40), but not of breast cancer (aHR 0.96, 95% CI 0.92-1.01). Ovarian cancer incidence was higher in women diagnosed with endometriosis, and in nulliparous women with ovulatory disturbances, compared to women with none of the diagnoses. Endometrial cancer incidence was higher in women with ovulatory disturbances, but not in women with endometriosis. These findings suggest that infertility could have long-term consequences of importance to physicians and public health workers.
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