ReviewEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2019
Microsurgery in musculoskeletal oncology.
Review in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Cost-effectiveness of microsurgical reconstructions in reconstructive plastic surgery within the Brazilian Public Health System: a 15-year overview (2009-2023).Einstein (Sao Paulo, Brazil) · 2026Article
- The role of orthoplastic surgery in musculoskeletal oncology.EFORT open reviews · 2025Review
- Imaging following surgery for primary appendicular bone tumours.Skeletal radiology · 2021Review
- Use of the Profunda Femoris Artery Perforator Flap for Reconstruction after Sarcoma Resection.Plastic and reconstructive surgery. Global open · 2020Article
- Oncological and endoprosthetic outcomes of bone sarcoma patients: a nationwide cohort study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2020Observational
- Pronator quadratus muscle flap: a preliminary cadaveric study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcomas are rare mesenchymal bone and soft tissue tumors of the musculoskeletal system. In the past, the primary treatment modality was amputation of the involved limb and the 5-year survival was very low for high-grade tumors. During the last three decades, limb salvage has become the rule rather than the exception and the use of neoadjuvant and adjuvant therapies (radiation and chemotherapy) has dramatically increased disease-free survival. Reconstruction of large bone and soft tissue defects, though, still remains a significant challenge in sarcoma patients. In particular, vascularized tissue transfer has proved extremely helpful in dealing with complex bone and soft tissue or functional defects that are frequently encountered as a result of the tumor or as a complication of surgery and adjuvant therapies. The principles, indications and results of microsurgical reconstruction differ from trauma patients and are directly related not only to the underlying disease process, but also to the local and systemic therapeutic modalities applied to the individual patient. Although plastic reconstruction in the oncological patients is not free of complications, usually these complications are manageable and do not jeopardize oncological outcome. The overall treatment strategy should be tailored to the patient's and sarcoma profile.
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Registered trials
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