ArticleJACC. Basic to translational science2018
Hydrogen Sulfide Attenuates Renin Angiotensin and Aldosterone Pathological Signaling to Preserve Kidney Function and Improve Exercise Tolerance in Heart Failure.
Erratum issuedOpen access · goldAbstract read
In one paragraph
Article in JACC. Basic to translational science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.
0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 43 citations in OpenAlex.
- Comparative Effects of Heart Failure Medications on Cardiac Remodeling via the Hydrogen Sulfide (HDiseases (Basel, Switzerland) · 2026Review
- Circulating pro-angiogenic cells are preserved despite myocardial angiogenic signal deficits in HFpEF model.Scientific reports · 2026Article
- Dysregulated ProteinCirculation research · 2025Article
- Hydrogen Sulfide Deficiency and Therapeutic Targeting in Cardiometabolic HFpEF: Evidence for Synergistic Benefit With GLP-1/Glucagon Agonism.JACC. Basic to translational science · 2025Article
- The bidirectional regulatory mechanism of gut microbiota metabolites on myocardial injury in heart failure from the perspective of the gut-heart axis: a review.Frontiers in microbiology · 2025Review
- Alcohol-induced gut microbial reorganization and associated overproduction of phenylacetylglutamine promotes cardiovascular disease.Nature communications · 2024Article
- Adjunctive therapy with an oral HBritish journal of pharmacology · 2024Article
- 2H-Thiopyran-2-thione sulfine, a compound for converting HNature communications · 2024Article
- Early Renal Denervation Attenuates Cardiac Dysfunction in Heart Failure With Preserved Ejection Fraction.Journal of the American Heart Association · 2024Article
- Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a "2-Hit" Murine Model.Journal of the American Heart Association · 2023Article
- Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart Failure.Circulation research · 2023Article
- Hydrogen sulfide donor activates AKT-eNOS signaling and promotes lymphatic vessel formation.PloS one · 2023Article
- The roles of hydrogen sulfide in renal physiology and disease states.Renal failure · 2022Review
- The Renin-Angiotensin-Aldosterone System, Nitric Oxide, and Hydrogen Sulfide at the Crossroads of Hypertension and COVID-19: Racial Disparities and Outcomes.International journal of molecular sciences · 2022Review
- Mitochondrial HCirculation research · 2022Article
- Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.Journal of cellular and molecular medicine · 2021Article
- Spatiotemporal regulation of hydrogen sulfide signaling in the kidney.Redox biology · 2021Review
- Hydrogen Sulfide as a Potential Therapy for Heart Failure-Past, Present, and Future.Antioxidants (Basel, Switzerland) · 2021Review
- Role of Oxidative Stress and Reduced Endogenous Hydrogen Sulfide in Diabetic Nephropathy.Drug design, development and therapy · 2021Article
- Hydrogen Sulfide and the Kidney.Advances in experimental medicine and biology · 2021Article
Corrections and comments
- Erratum issuedCorrection.2019
Authors and funding
10 authors at 3 institutions in 1 country.
Zhen LiCardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Chelsea L OrganCardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Jianming KangDepartment of Chemistry, Washington State University, Pullman, Washington.
David J PolhemusCardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Rishi K TrivediCardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Thomas E SharpCardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Jack S JenkinsCardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Ya-Xiong TaoDepartment of Anatomy, Physiology, and Pharmacology, Auburn University College of Veterinary Medicine, Auburn, Alabama.
Ming XianDepartment of Chemistry, Washington State University, Pullman, Washington.
David J LeferCardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Louisiana State University Health Sciences Center New Orleans · USWashington State University · USAuburn University · US
Funding
Preclinical Consortium to Facilitate Translation of Cardioprotective TherapiesU24HL094373 · NHLBI · UNIVERSITY OF LOUISVILLE · PI BOLLI, ROBERTO · 2010 to 2014
$9.6MCardioprotective Actions of Hydrogen SulfideR01HL092141 · NHLBI · LSU HEALTH SCIENCES CENTER · PI LEFER, DAVID JOSEPH · 2009 to 2013
$1.9MNovel Sulfide Releasing Agents for Ischemic InjuryR01HL116571 · NHLBI · WASHINGTON STATE UNIVERSITY · PI LEFER, DAVID JOSEPH, XIAN, MING · 2014 to 2017
$1.8MNitrite Mediated CardioprotectionR01HL093579 · NHLBI · LSU HEALTH SCIENCES CENTER · PI LEFER, DAVID JOSEPH · 2009 to 2012
$1.5MNHLBI NIH HHS R01 HL092141NHLBI NIH HHS R01 HL093579NHLBI NIH HHS R01 HL116571NHLBI NIH HHS U24 HL094373
Abstract
Cardioprotective effects of H
Indexed as
BNP, B-type natriuretic peptidecardiorenal syndromecGMP, cyclic guanosine monophosphateexercise toleranceheart failureHF, heart failurehydrogen sulfideLVEF, left ventricular ejection fractionRAASRAAS, renin-angiotensin-aldosterone systemSNS, sympathetic nervous systemTAC, transverse aortic constriction
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.