ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2019
Normative data from linear and nonlinear quantile regression in CANTAB: Cognition in mid-to-late life in an epidemiological sample.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
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- Global scale-free brain activity as a potential neural signature of visual information processing in aging.Frontiers in aging neuroscience · 2026Article
- Nonlinear Lifespan Trajectories of Memory and Fluid Reasoning: A Longitudinal GAMM Study.Research square · 2025Article
- Review
- Computerized assessment of neuropsychological functioning in pediatric brain tumor patients.Journal of neuro-oncology · 2025Article
- Assessing the determinants and association of cognitive memory performance with blood folate and cobalamin levels in Qatar's healthy aging population.Qatar medical journal · 2025Article
- Cognitive outcomes after tadalafil treatment in patients with cerebral small vessel disease: ETLAS-2 sub-study.Cerebral circulation - cognition and behavior · 2025Article
- The Hidden Dangers of Sedentary Living: Insights into Molecular, Cellular, and Systemic Mechanisms.International journal of molecular sciences · 2024Review
- A study of long-term supraphysiologic-dose anabolic-androgenic steroid use on cognitive function in middle-aged men.The American journal of drug and alcohol abuse · 2024Article
- Unsupervised Online Paired Associates Learning Task from the Cambridge Neuropsychological Test Automated Battery (CANTAB®) in the Brain Health Registry.The journal of prevention of Alzheimer's disease · 2024Article
- Generating normative data from web-based administration of the Cambridge Neuropsychological Test Automated Battery using a Bayesian framework.Frontiers in digital health · 2024Article
- H-coil repetitive transcranial magnetic stimulation does not improve executive function in patients with chronic peripheral neuropathic pain: a randomized sham-controlled crossover study.Frontiers in psychiatry · 2024Article
- Associations of Perceived Stress and Psychological Resilience With Cognition and a Modifiable Dementia Risk Score in Middle-Aged Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Article
- Impact of sleep deprivation on neurocognition and inflammation in rhesus macaques.Brain, behavior, & immunity - health · 2023Article
- Article
- Neurocognitive impact of Zika virus infection in adult rhesus macaques.Journal of neuroinflammation · 2022Article
- Resting-state electroencephalographic correlates of cognitive reserve: Moderating the age-related worsening in cognitive function.Frontiers in aging neuroscience · 2022Article
- Gait variability predicts cognitive impairment in older adults with subclinical cerebral small vessel disease.Frontiers in aging neuroscience · 2022Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionNormative cognitive data can help to distinguish pathological decline from normal aging. This study presents normative data from the Cambridge Neuropsychological Test Automated Battery, using linear regression and nonlinear quantile regression approaches.
methodsHeinz Nixdorf Recall study participants completed Cambridge Neuropsychological Test Automated Battery tests: paired-associate learning, spatial working memory, and reaction time. Data were available for 1349-1529 healthy adults aged 57-84 years. Linear and nonlinear quantile regression analyses examined age-related changes, adjusting for sex and education. Quantile regression differentiated seven performance bands (percentiles: 97.7, 93.3, 84.1, 50, 15.9, 6.7, and 2.3).
resultsNormative data show age-related cognitive decline across all tests, but with quantile regression revealing heterogeneous trajectories of cognitive aging, particularly for the test of episodic memory function (paired-associate learning). DISCUSSION: This study presents normative data from Cambridge Neuropsychological Test Automated Battery in mid-to-late life. Quantile regression can model heterogeneity in age-related cognitive trajectories as seen in the paired-associate learning episodic memory measure.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.