Evidence map›Paper›PMID 30622981›Full record

ArticleJournal of immunology research2018

An O-Antigen Glycoconjugate Vaccine Produced Using Protein Glycan Coupling Technology Is Protective in an Inhalational Rat Model of Tularemia.

Laura E Marshall, Michelle Nelson, Carwyn H Davies, Adam O Whelan, Dominic C Jenner, Madeleine G Moule, Carmen Denman, Jon Cuccui, Timothy P Atkins, Brendan W Wren and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Laura E MarshallDefence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Michelle NelsonDefence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Carwyn H DaviesDefence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Adam O WhelanDefence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.ORCID 0000-0003-1027-9538
Dominic C JennerDefence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Madeleine G MouleDepartment of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Carmen DenmanDepartment of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Jon CuccuiDepartment of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Timothy P AtkinsDefence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.ORCID 0000-0002-5880-0866
Brendan W WrenDepartment of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Joann L PriorDefence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.ORCID 0000-0003-1779-8154
Defence Science and Technology Laboratory · GBUniversity of London · GB

Funding

Medical Research Council MR/K012053/1Wellcome Trust 102979/Z/13/Z
6 · The paper itself

Abstract

There is a requirement for an efficacious vaccine to protect people against infection from

Indexed as

AnimalsBacterial VaccinesCells, CulturedDisease Models, AnimalFemaleFrancisella tularensisGlycoconjugatesHexosyltransferasesHumansInhalationMiceMice, Inbred BALB CProtein BindingPseudomonas aeruginosaRatsRats, Inbred F344Bacterial VaccinesGlycoconjugatesHexosyltransferasesO-antigen polymerase

Identifiers

PMID30622981
PMCPMC6304830
OpenAlexW2903564878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.