Evidence map›Paper›PMID 30622836›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2018

Anti-GAD Antibody-associated Syndrome Presenting with Limb Myoclonus.

Pedro Manzke, Talyta Grippe, Georgia L Tavares, Lucas C Leal, Emmanuel Roze, Emmanuelle Apartis, Ronaldo Maciel Dias, André G F Ferreira

Open access · greenAbstract readCase Reports
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Pedro ManzkeDepartment of Neurology, Instituto Hospital de Base do Distrito Federal, Brasília, BR.
Talyta GrippeDepartment of Neurology, Instituto Hospital de Base do Distrito Federal, Brasília, BR.
Georgia L TavaresDepartment of Neurology, Instituto Hospital de Base do Distrito Federal, Brasília, BR.
Lucas C LealDepartment of Neurology, Instituto Hospital de Base do Distrito Federal, Brasília, BR.
Emmanuel RozeAP-HP, Department of Neurology, Pitié-Salpêtrière Hospital, Paris, FR.
Emmanuelle ApartisAP-HP, Department of Neurology, Pitié-Salpêtrière Hospital, Paris, FR.
Ronaldo Maciel DiasDepartment of Neurology, Instituto Hospital de Base do Distrito Federal, Brasília, BR.
André G F FerreiraDepartment of Neurology, Instituto Hospital de Base do Distrito Federal, Brasília, BR.
Hospital de Base · BRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The clinical spectrum of anti-glutamic acid decarboxylase (GAD) antibody-associated neurologic syndromes is expanding, with focal, generalized, and atypical forms. Case Report: We describe a 59-year-old female showing continuous right lower limb myoclonus and mild encephalopathy. These symptoms started 2 weeks prior to evaluation. The patient had great improvement with intravenous steroids. An autoantibody panel was positive for anti-GAD. Discussion: Various clinical manifestations, including myoclonus, may relate to anti-GAD antibodies. The treatment options available include symptomatic drugs, intravenous immunoglobulin, steroids, and other immunosuppressant agents.

Indexed as

AutoantibodiesBiomarkersFemaleGlucocorticoidsGlutamate DecarboxylaseHumansLegMethylprednisoloneMiddle AgedMyoclonusAutoantibodiesBiomarkersGlucocorticoidsGlutamate DecarboxylaseMethylprednisoloneAnti-glutamic acid decarboxylase antibodiesautoimmunityepilepsymyoclonusstiff person syndrome

Identifiers

PMID30622836
PMCPMC6315060
OpenAlexW2899446132

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.