Evidence map›Paper›PMID 30622787›Full record

ArticleJournal of thoracic disease2018

Unidirectional endobronchial valves for management of persistent air-leaks: results of a multicenter study.

Alfonso Fiorelli, Antonio D'Andrilli, Roberto Cascone, Luisa Occhiati, Marco Anile, Daniele Diso, Francesco Cassiano, Camilla Poggi, Mohsen Ibrahim, Giacomo Cusumano and 11 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of thoracic disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 64 citations in OpenAlex.

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  16. One-Way Endobronchial Valves as Management for Persistent Air Leaks: A Preview of What's to Come?American journal of respiratory and critical care medicine · 2019
    Article
  17. Article
  18. Article
  19. Management of air leaks post-surgical lung resection.Annals of translational medicine · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 1 country.

Alfonso FiorelliThoracic Surgery Unit, Università della Campania "Luigi Vanvitelli", Naples, Italy.
Antonio D'AndrilliThoracic Surgery Unit, Università La Sapienza, Sant'Andrea Hospital, Rome, Italy.
Roberto CasconeThoracic Surgery Unit, Università della Campania "Luigi Vanvitelli", Naples, Italy.
Luisa OcchiatiThoracic Surgery Unit, Università della Campania "Luigi Vanvitelli", Naples, Italy.
Marco AnileThoracic Surgery Unit, Università La Sapienza, Policlinico Hospital, Rome, Italy.
Daniele DisoThoracic Surgery Unit, Università La Sapienza, Policlinico Hospital, Rome, Italy.
Francesco CassianoThoracic Surgery Unit, Università La Sapienza, Sant'Andrea Hospital, Rome, Italy.
Camilla PoggiThoracic Surgery Unit, Università La Sapienza, Sant'Andrea Hospital, Rome, Italy.
Mohsen IbrahimThoracic Surgery Unit, Università La Sapienza, Sant'Andrea Hospital, Rome, Italy.
Giacomo CusumanoThoracic Surgery Unit, Policlinico Vittorio Emanuele Hospital, Catania, Italy.
Alberto TerminellaThoracic Surgery Unit, Policlinico Vittorio Emanuele Hospital, Catania, Italy.
Giuseppe FaillaInterventional Pneumology Unit, Ospedale Civico Palermo, Palermo, Italy.
Alba La SalaInterventional Pneumology Unit, Ospedale Civico Palermo, Palermo, Italy.
Michela BezziInterventional Pneumology Unit, Policlinico Firenze, Florence, Italy.
Margherita InnocentiInterventional Pneumology Unit, Policlinico Firenze, Florence, Italy.
Elena TorricelliInterventional Pneumology Unit, Policlinico Firenze, Florence, Italy.
Federico VenutaThoracic Surgery Unit, Università La Sapienza, Policlinico Hospital, Rome, Italy.
Erino Angelo RendinaThoracic Surgery Unit, Università La Sapienza, Sant'Andrea Hospital, Rome, Italy.
Giovanni VicidominiThoracic Surgery Unit, Università della Campania "Luigi Vanvitelli", Naples, Italy.
Mario SantiniThoracic Surgery Unit, Università della Campania "Luigi Vanvitelli", Naples, Italy.
Claudio AndreettiThoracic Surgery Unit, Università La Sapienza, Sant'Andrea Hospital, Rome, Italy.
Azienda Ospedaliera Sant'Andrea · ITUniversity of Campania "Luigi Vanvitelli" · ITAzienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the efficacy of Endo-Bronchial Valves in the management of persistent air-leaks (PALs) and the procedural cost.

methodsIt was a retrospective multicenter study including consecutive patients with PALs for alveolar pleural fistula (APF) undergoing valve treatment. We assessed the efficacy and the cost of the procedure.

resultsSeventy-four patients with persistent air leaks due to various etiologies were included in the analysis. In all cases the air leaks were severe and refractory to standard treatments. Sixty-seven (91%) patients underwent valve treatment obtaining a complete resolution of air-leaks in 59 (88%) patients; a reduction of air-leaks in 6 (9%); and no benefits in 2 (3%). The comparison of data before and after valve treatment showed a significant reduction of air-leak duration (16.2±8.8 versus 5.0±1.7 days; P<0.0001); chest tube removal (16.2±8.8 versus 7.3±2.7 days; P<0.0001); and length of hospital stay (LOS) (16.2±8.8 versus 9.7±2.8 days; P=0.004). Seven patients not undergoing valve treatment underwent pneumo-peritoneum with pleurodesis (n=6) or only pleurodesis (n=1). In only 1 (14%) patient, the chest drainage was removed 23 days later while the remaining 6 (86%) were discharged with a domiciliary chest drainage removed after 157±41 days. No significant difference was found in health cost before and after endobronchial valve (EBV) implant (P=0.3).

conclusionsValve treatment for persistent air leaks is an effective procedure. The reduction of hospitalization costs related to early resolution of air-leaks could overcome the procedural cost.

Indexed as

alveolar-pleural fistulabronchoscopypersistent air-leak (PAL)Zephyr endobronchial valves (Zephyr EBV)

Identifiers

PMID30622787
PMCPMC6297418
OpenAlexW2899129086

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.