ArticleJournal of thoracic disease2018
Is adjuvant antifungal therapy after video-assisted thoracic surgery for pulmonary aspergilloma necessary?
Article in Journal of thoracic disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Pulmonary Aspergillus Nodule in an Immunocompetent Host: A Case Report.Clinical case reports · 2026Article
- Pulmonary aspergillosis diagnosed during surgical treatment for spontaneous pneumothorax: a case report.AME case reports · 2026Article
- Surgical Treatment for Pulmonary Aspergillosis: A Thirty-Year Single-Center Experience and the Contemporary Role of Surgery.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026Article
- Recurrent Verruconis gallopava Infection at One Year after Excision of a Solitary Pulmonary Lesion.Internal medicine (Tokyo, Japan) · 2024Article
- Outcomes of surgery for different types of chronic pulmonary aspergillosis: results from a single-center, retrospective cohort study.BMC pulmonary medicine · 2022Article
- Clinical Characteristics and Treatment Outcomes of Pathologically ConfirmedJournal of clinical medicine · 2020Article
- The fate of aspergilloma patients after surgical treatment-experience from 22 cases.Journal of thoracic disease · 2019Article
- Chronic pulmonary aspergillosis: comprehensive insights into epidemiology, treatment, and unresolved challenges.Therapeutic advances in infectious diseaseReview
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this current retrospective study was to assess the necessity of postoperative antifungal therapy for pulmonary aspergilloma (PA) patients who underwent video-assisted thoracic surgery (VATS) lung resection.
methodsWe enrolled 22 PA patients who underwent VATS lung resection between 2014 and 2018. Of these, 12 patients were prescribed antifungal agents during the perioperative period (group A), and the other 10 were treated with surgery alone without any antifungal therapy postoperatively (group B). All patients were immunocompetent.
resultsSeven patients (58.3%) developed postoperative complications in group A, including 2 cases of empyema (16.7%), 1 case of bronchopleural fistula (8.3%), 1 case of pneumonia (8.3%), 1 case of wound infection (8.3%), 1 case of bleeding (8.3%) and 1 case of atelectasis (8.3%). In group B, 3 patients (30%) developed postoperative complications, including 2 cases of pneumonia (20%) and 1 case of empyema (10%). There was no significant difference between the groups with respect to postoperative complications rates (P=0.23). The follow-up period ranged from 1 to 38 months (a median of 19 months), during which no hospital deaths, recurrence of disease or lesion relapses were noted in either group.
conclusionsOur results suggested that postoperative adjuvant antifungal therapy has limited advantages for the surgical treatment of PA in immunocompetent patients.
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