Evidence map›Paper›PMID 30622740›Full record

ArticleNPJ Regenerative medicine2019

Relative contributions of adipose-resident CD146

Yiyun Wang, Jiajia Xu, Leslie Chang, Carolyn A Meyers, Lei Zhang, Kristen Broderick, Min Lee, Bruno Peault, Aaron W James

Open access · goldAbstract read
In one paragraph

Article in NPJ Regenerative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 73 citations in OpenAlex.

  1. Revisiting MSC heterogeneity: significance of the CD73Frontiers in bioengineering and biotechnology · 2026
    Article
  2. Article
  3. Pericytes in the optic nerve head.Progress in retinal and eye research · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Differential pericyte marker expression in craniofacial benign and malignant vascular tumors.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Blood Vessel Resident Human Stem Cells in Health and Disease.Stem cells translational medicine · 2022
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Yiyun Wang1Department of Pathology, Johns Hopkins University, 21205 Baltimore, MD USA.
Jiajia Xu1Department of Pathology, Johns Hopkins University, 21205 Baltimore, MD USA.ORCID 0000-0002-6084-2029
Leslie Chang1Department of Pathology, Johns Hopkins University, 21205 Baltimore, MD USA.
Carolyn A Meyers1Department of Pathology, Johns Hopkins University, 21205 Baltimore, MD USA.
Lei Zhang1Department of Pathology, Johns Hopkins University, 21205 Baltimore, MD USA.
Kristen Broderick2Department of Plastic Surgery, Johns Hopkins University, 21205 Baltimore, MD USA.
Min Lee3School of Dentistry, University of California, Los Angeles, 90095 CA USA.
Bruno Peault4UCLA and Orthopaedic Hospital Department of Orthopaedic Surgery, Orthopaedic Hospital Research Center, 90095 Los Angeles, CA USA.
Aaron W James1Department of Pathology, Johns Hopkins University, 21205 Baltimore, MD USA.
Johns Hopkins University · USMRC Centre for Regenerative Medicine · GBUniversity of California, Los Angeles · US

Funding

Direct and indirect contributions of perivascular stem cells to bone healingR01AR070773 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI JAMES, AARON W · 2017 to 2021
$1.4M
NELL-1 isoforms for the systemic treatment of osteoporosisK08AR068316 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JAMES, AARON W · 2015 to 2019
$534k
Role of sensory nerves in cranial bone repairR21DE027922 · NIDCR · JOHNS HOPKINS UNIVERSITY · PI CLEMENS, THOMAS L, JAMES, AARON W · 2018 to 2019
$450k
Medical Research Council G1000816NIAMS NIH HHS K08 AR068316NIAMS NIH HHS R01 AR070773NIDCR NIH HHS R21 DE027922
6 · The paper itself

Abstract

Pericytes and other perivascular stem/stromal cells are of growing interest in the field of tissue engineering. A portion of perivascular cells are well recognized to have MSC (mesenchymal stem cell) characteristics, including multipotentiality, self-renewal, immunoregulatory functions, and diverse roles in tissue repair. Here, we investigate the differential but overlapping roles of two perivascular cell subsets in paracrine induction of bone repair. CD146

Identifiers

PMID30622740
PMCPMC6323123
OpenAlexW2907441295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.