Evidence map›Paper›PMID 30622707›Full record

ReviewAnnals of medicine and surgery (2012)2019

Autologous fat grafting: Latest insights.

Maarten Doornaert, Julien Colle, Elisabeth De Maere, Heidi Declercq, Phillip Blondeel

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05464290 (Nonfat Grafting in Male and Female Genital Lichen Sclerosus), which is not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05464290 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Nonfat Grafting in Male and Female Genital Lichen Sclerosus

TypeinterventionalSponsorUniversity of Roma La SapienzaRan2022 to 2023Enrolled25ConditionsUrethral StrictureArmsNANOfat grafting
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maarten DoornaertUniversity Hospital Gent, Belgium.
Julien ColleUniversity Hospital Gent, Belgium.
Elisabeth De MaereUniversity Hospital Gent, Belgium.
Heidi DeclercqUniversity Hospital Gent, Belgium.
Phillip BlondeelUniversity Hospital Gent, Belgium.
Ghent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A recent rise in the use of autologous fat transfer for soft tissue augmentation has paralleled the increasing popularity of liposuction body contouring. This creates a readily available and inexpensive product for lipografting, which is the application of lipoaspirated material. Consistent scientific proof about the long-term viability of the transferred fat is not available. Clinically, there is a reabsorption rate which has been reported to range from 20 to 90%. Results can be unpredictable with overcorrection and regular need for additional interventions. In this review, adipogenesis physiology and the adipogenic cascade from adipose-derived stem cells to adult adipocytes is extensively described to determine various procedures involved in the fat grafting technique. Variables in structure and physiology, adipose tissue harvesting- and processing techniques, and the preservation of fat grafts are taken into account to collect reproducible scientific data to establish standard in vitro and in vivo models for experimental fat grafting. Adequate histological staining for fat tissue, immunohistochemistry and viability assays should be universally used in experiments to be able to produce comparative results. By analysis of the applied methods and comparison to similar experiments, a conclusion concerning the ideal technique to improve clinical outcome is proposed.

Indexed as

ASCCALCellFat graftingLipofillingLipotransferWhite adipose tissue engineering

Identifiers

PMID30622707
PMCPMC6318549
OpenAlexW2896249608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.