Evidence map›Paper›PMID 30622546›Full record

ReviewFrontiers in plant science2018

Revisiting Risk Governance of GM Plants: The Need to Consider New and Emerging Gene-Editing Techniques.

Sarah Z Agapito-Tenfen, Arinze S Okoli, Michael J Bernstein, Odd-Gunnar Wikmark, Anne I Myhr

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in plant science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 81 citations in OpenAlex.

  1. Review
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  5. 3 Biotech · 2024
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  20. Genome Editing in Cereals: Approaches, Applications and Challenges.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sarah Z Agapito-TenfenGenØk - Centre for Biosafety, SIVA Innovation Centre, Tromsø, Norway.
Arinze S OkoliGenØk - Centre for Biosafety, SIVA Innovation Centre, Tromsø, Norway.
Michael J BernsteinGenØk - Centre for Biosafety, SIVA Innovation Centre, Tromsø, Norway.
Odd-Gunnar WikmarkGenØk - Centre for Biosafety, SIVA Innovation Centre, Tromsø, Norway.
Anne I MyhrGenØk - Centre for Biosafety, SIVA Innovation Centre, Tromsø, Norway.
GenØk · NONorth-West University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New and emerging gene-editing techniques make it possible to target specific genes in species with greater speed and specificity than previously possible. Of major relevance for plant breeding, regulators and scientists are discussing how to regulate products developed using these gene-editing techniques. Such discussions include whether to adopt or adapt the current framework for GMO risk governance in evaluating the impacts of gene-edited plants, and derived products, on the environment, human and animal health and society. Product classification or definition is one of several aspects of the current framework being criticized. Further, knowledge gaps related to risk assessments of gene-edited organisms-for example of target and off-target effects of intervention in plant genomes-are also of concern. Resolving these and related aspects of the current framework will involve addressing many subjective, value-laden positions, for example how to specify protection goals through ecosystem service approaches. A process informed by responsible research and innovation practices, involving a broader community of people, organizations, experts, and interest groups, could help scientists, regulators, and other stakeholders address these complex, value-laden concerns related to gene-editing of plants with and for society.

Indexed as

CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9crop breedinggenetically modified plantsrisk assessmenttransgenic plants

Identifiers

PMID30622546
PMCPMC6308909
OpenAlexW2905729922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.