Evidence map›Paper›PMID 30622531›Full record

ArticleFrontiers in immunology2018

CD103 (αE Integrin) Undergoes Endosomal Trafficking in Human Dendritic Cells, but Does Not Mediate Epithelial Adhesion.

Steve Swain, Mandi M Roe, Thomas A Sebrell, Barkan Sidar, Jennifer Dankoff, Rachel VanAusdol, Lesley E Smythies, Phillip D Smith, Diane Bimczok

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Physical, chemical, and structural properties of human gastric organoid-derived mucus.American journal of physiology. Gastrointestinal and liver physiology · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Steve SwainDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, United States.
Mandi M RoeDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, United States.
Thomas A SebrellDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, United States.
Barkan SidarChemical and Biological Engineering Department, Montana State University, Bozeman, MT, United States.
Jennifer DankoffDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, United States.
Rachel VanAusdolDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, United States.
Lesley E SmythiesDivision of Gastroenterology and Hepatology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Phillip D SmithDivision of Gastroenterology and Hepatology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Diane BimczokDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, United States.
Montana State University · USUniversity of Alabama at Birmingham · US

Funding

Pilot Grants ProgramP30GM110732 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI JUTILA, MARK A · 2014 to 2018
$5.4M
Dendritic Cell-Epithelial Cell Crosstalk in Human H. pylori GastritisK01DK097144 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BIMCZOK, DIANE · 2012 to 2015
$490k
Harnessing human gastric organoids to investigate the role of CD103 in gastric dendritic cell – epithelial cell crosstalkR03DK107960 · NIDDK · MONTANA STATE UNIVERSITY - BOZEMAN · PI BIMCZOK, DIANE · 2015 to 2016
$144k
NIDDK NIH HHS K01 DK097144NIDDK NIH HHS R03 DK107960NIGMS NIH HHS P30 GM110732
6 · The paper itself

Abstract

Dendritic cell (DC) expression of CD103, the α subunit of αEβ7 integrin, is thought to enable DC interactions with E-cadherin-expressing gastrointestinal epithelia for improved mucosal immunosurveillance. In the stomach, efficient DC surveillance of the epithelial barrier is crucial for the induction of immune responses to

Indexed as

Immunity, MucosalAdultAntigens, CDCadherinsCell AdhesionCell CommunicationCells, CulturedDendritic CellsEndosomesEpithelial CellsGastric MucosaHealthy VolunteersHelicobacter InfectionsHelicobacter pyloriHumansIntegrin alpha Chainsalpha E integrinsAntigens, CDCadherinsCDH1 protein, humanIntegrin alpha ChainsTretinoinantigen-presenting cellcell adhesionendosomegastrointestinal epitheliumintegrin alpha E

Identifiers

PMID30622531
PMCPMC6308147
OpenAlexW2906105031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.