Evidence map›Paper›PMID 30622481›Full record

ArticleFrontiers in physiology2018

Dietary Creatine Supplementation in Gilthead Seabream (

Denise Schrama, Marco Cerqueira, Claúdia S Raposo, Ana M Rosa da Costa, Tune Wulff, Amparo Gonçalves, Carolina Camacho, Rita Colen, Flávio Fonseca, Pedro M Rodrigues

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Thermal and Nutritional Strategies for ManagingAnimals : an open access journal from MDPI · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. DIGE Analysis of Fish Tissues.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Denise SchramaCentro de Ciências do Mar, Universidade do Algarve, Faro, Portugal.
Marco CerqueiraCentro de Ciências do Mar, Universidade do Algarve, Faro, Portugal.
Claúdia S RaposoCentro de Ciências do Mar, Universidade do Algarve, Faro, Portugal.
Ana M Rosa da CostaCentro de Investigação de Química do Algarve, Universidade do Algarve, Faro, Portugal.
Tune WulffNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark.
Amparo GonçalvesDivisão de Aquacultura e Valorização, Instituto Português do Mar e da Atmosfera, Lisbon, Portugal.
Carolina CamachoDivisão de Aquacultura e Valorização, Instituto Português do Mar e da Atmosfera, Lisbon, Portugal.
Rita ColenCentro de Ciências do Mar, Universidade do Algarve, Faro, Portugal.
Flávio FonsecaInstituto Federal de Educação, Ciência e Tecnologia do Amazonas, Manaus, Brazil.
Pedro M RodriguesCentro de Ciências do Mar, Universidade do Algarve, Faro, Portugal.
University of Algarve · PTPortuguese Sea and Atmosphere Institute · PTInstituto Federal do Amazonas · BRTechnical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quality of fish flesh depends on the skeletal muscle's energetic state and delaying energy depletion through diets supplementation could contribute to the preservation of muscle's quality traits and modulation of fish allergens. Food allergies represent a serious public health problem worldwide with fish being one of the top eight more allergenic foods. Parvalbumins, have been identified as the main fish allergen. In this study, we attempted to produce a low allergenic farmed fish with improved muscle quality in controlled artificial conditions by supplementing a commercial fish diet with different creatine percentages. The supplementation of fish diets with specific nutrients, aimed at reducing the expression of parvalbumin, can be considered of higher interest and beneficial in terms of food safety and human health. The effects of these supplemented diets on fish growth, physiological stress, fish muscle status, and parvalbumin modulation were investigated. Data from zootechnical parameters were used to evaluate fish growth, food conversion ratios and hepatosomatic index. Physiological stress responses were assessed by measuring cortisol releases and muscle quality analyzed by

Indexed as

aquaculturecreatinefish nutritiongilthead seabreammuscle qualityparvalbuminproteomics

Identifiers

PMID30622481
PMCPMC6308192
OpenAlexW2906479610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.