ArticleFood & nutrition research2018
Oolong tea polysaccharide and polyphenols prevent obesity development in Sprague-Dawley rats.
Article in Food & nutrition research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 39 citations in OpenAlex.
- Adipose Tissue Aging and Natural Interventions: Potential Roles of Polyphenols and Polysaccharides.Nutrients · 2026Review
- The Influence and Mechanisms of Natural Plant Polysaccharides on Intestinal Microbiota-Mediated Metabolic Disorders.Foods (Basel, Switzerland) · 2024Review
- In Vivo Tissue Distribution and Pharmacokinetics of FITC-LabelledFoods (Basel, Switzerland) · 2024Article
- Ultrasonic-Assisted Extraction and Gastrointestinal Digestion Characteristics of Polysaccharides Extracted fromFoods (Basel, Switzerland) · 2024Article
- Article
- Advances in the Utilization of Tea Polysaccharides: Preparation, Physicochemical Properties, and Health Benefits.Polymers · 2022Review
- Oolonghomobisflavans from Camellia sinensis increase Caenorhabditis elegans lifespan and healthspan.GeroScience · 2022Article
- Sensory and chemical characteristics ofFood chemistry: X · 2021Article
- Role of Herbal Teas in Regulating Cellular Homeostasis and Autophagy and Their Implications in Regulating Overall Health.Nutrients · 2021Review
- Effects of Oil Tea on Obesity and Dyslipidemia: A Cross-Sectional Study in China.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies have evaluated the effects of oolong tea extracts on obesity. However, only few studies focused on the anti-obesity effect of specific components of oolong tea.
objectiveThis study investigated the specific anti-obesity capabilities of oolong tea polysaccharide (TPS) and tea polyphenols (TPP) in high-fat diet-induced Sprague-Dawley rats.
methodsOolong tea water extract, TPS, TPP, and polysaccharide mixed with polyphenol (TPSM) given at doses of 400 or 800 mg/kg were administered to rats fed with high-fat diet for 6 weeks to explore the anti-obesity effects of the treatments.
resultsTPS and TPP were responsible for the suppressive effect on body fat accumulation. TPSM exhibited the highest effect on body weight reduction, and TPS and TPP effectively reduced serum leptin levels and significantly improved blood lipid and antioxidant levels. Moreover, microarray analysis of hepatic and adipose gene expression profiles revealed that TPP and TPS inhibited obesity through effects on the pathways of fatty acid biosynthesis, steroid hormone biosynthesis, unsaturated fatty acid biosynthesis, fatty acid elongation, glycerolipid metabolism, and glycerophospholipid metabolism.
conclusionsTPSM might be a potential therapy for the treatment of obesity.
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