Evidence map›Paper›PMID 30622315›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2019

Importance of the commissural nucleus of the solitary tract in renovascular hypertension.

Mariana Rosso Melo, Silvia Gasparini, Guilherme F Speretta, Elaine Fernanda Silva, Gustavo Rodrigues Pedrino, Jose V Menani, Daniel B Zoccal, Débora Simões Almeida Colombari, Eduardo Colombari

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The Controversial Roles of Areca Nut: Medicine or Toxin?International journal of molecular sciences · 2023
    Review
  5. Review
  6. Article
  7. Unilateral vagotomy alters astrocyte and microglial morphology in the nucleus tractus solitarii of the rat.American journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Article
  8. Review
  9. Melatonin as a rational alternative in the conservative treatment of resistant hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mariana Rosso MeloDepartment of Physiology and Pathology, School of Dentistry, São Paulo State University, UNESP, Araraquara, SP, Brazil.
Silvia GaspariniDepartment of Physiology and Pathology, School of Dentistry, São Paulo State University, UNESP, Araraquara, SP, Brazil.
Guilherme F SperettaDepartment of Physiology and Pathology, School of Dentistry, São Paulo State University, UNESP, Araraquara, SP, Brazil.
Elaine Fernanda SilvaCenter for Neuroscience and Cardiovascular Research, Department of Physiological Sciences, Biological Sciences Institute, Federal University of Goiás, Goiânia, Goiás, Brazil.
Gustavo Rodrigues PedrinoCenter for Neuroscience and Cardiovascular Research, Department of Physiological Sciences, Biological Sciences Institute, Federal University of Goiás, Goiânia, Goiás, Brazil.
Jose V MenaniDepartment of Physiology and Pathology, School of Dentistry, São Paulo State University, UNESP, Araraquara, SP, Brazil.
Daniel B ZoccalDepartment of Physiology and Pathology, School of Dentistry, São Paulo State University, UNESP, Araraquara, SP, Brazil.
Débora Simões Almeida ColombariDepartment of Physiology and Pathology, School of Dentistry, São Paulo State University, UNESP, Araraquara, SP, Brazil.
Eduardo ColombariDepartment of Physiology and Pathology, School of Dentistry, São Paulo State University, UNESP, Araraquara, SP, Brazil. eduardo.colombari@unesp.br.
Universidade Estadual Paulista (Unesp) · BRUniversidade Federal de Goiás · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rodent renovascular hypertension model has been used to investigate the mechanisms promoting hypertension. The importance of the carotid body for renovascular hypertension has been demonstrated. As the commissural NTS (cNTS) is the first synaptic site in the central nervous system that receives information from carotid body chemoreceptors, we evaluated the contribution of cNTS to renovascular hypertension in the present study. Normotensive male Holtzman rats were implanted with a silver clip around the left renal artery to induce two-kidney, one-clip (2K1C) hypertension. Six weeks later, isoguvacine (a GABA

Indexed as

Angiotensin II Type 1 Receptor BlockersAnimalsCarotid BodyHypertension, RenovascularMaleRats, Sprague-DawleySolitary NucleusAngiotensin II Type 1 Receptor Blockersangiotensin IIAT1 subtype receptorcommissural NTSrenal hypertension

Identifiers

PMID30622315
OpenAlexW2909367283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.