Evidence map›Paper›PMID 30622231›Full record

ArticleMolecules and cells2019

OCT4B Isoform Promotes Anchorage-Independent Growth of Glioblastoma Cells.

Sang-Hun Choi, Jun-Kyum Kim, Hee-Young Jeon, Kiyoung Eun, Hyunggee Kim

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules and cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sang-Hun ChoiDepartment of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Korea.
Jun-Kyum KimDepartment of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Korea.
Hee-Young JeonDepartment of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Korea.
Kiyoung EunDepartment of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Korea.
Hyunggee KimDepartment of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Korea.
Korea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

OCT4, also known as POU5F1 (POU domain class 5 transcription factor 1), is a transcription factor that acts as a master regulator of pluripotency in embryonic stem cells and is one of the reprogramming factors required for generating induced pluripotent stem cells. The human OCT4 encodes three isoforms, OCT4A, OCT4B, and OCT4B1, which are generated by alternative splicing. Currently, the functions and expression patterns of OCT4B remain largely unknown in malignancies, especially in human glioblastomas. Here, we demonstrated the function of OCT4B in human glioblastomas. Among the isoform of OCT4B, OCT4B-190 (OCT4B

Indexed as

Cell AdhesionCell Line, TumorCell NucleusCell ProliferationGene Expression Regulation, NeoplasticGlioblastomaHumansOctamer Transcription Factor-3PrognosisProtein IsoformsStress, PhysiologicalTumor Stem Cell AssayOctamer Transcription Factor-3POU5F1 protein, humanProtein Isoformsanchorage-independent growthcytoplasmic localizationglioblastomamechanical stress responseOCT4B

Identifiers

PMID30622231
PMCPMC6399006
OpenAlexW2946785258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.