Evidence map›Paper›PMID 30622189›Full record

ArticlemBio2019

Three

Yifan Wang, Kimberly M Cirelli, Patricio D C Barros, Lamba Omar Sangaré, Vincent Butty, Musa A Hassan, Patricia Pesavento, Asli Mete, Jeroen P J Saeij

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Virulence · 2026
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  3. A pooled image-based CRISPR screen identifies EAF1 as abioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Dense granule proteins: key mediators ofFrontiers in medicine · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. TwomBio · 2024
    Article
  16. Article
  17. Host E3 ubiquitin ligase ITCH mediatesbioRxiv : the preprint server for biology · 2023
    Article
  18. GRA47 and GRA72 arebioRxiv : the preprint server for biology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Yifan Wang *Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Kimberly M Cirelli *Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Patricio D C BarrosDepartment of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Lamba Omar SangaréDepartment of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Vincent ButtyDepartment of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Musa A HassanCollege of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, United Kingdom.
Patricia PesaventoDepartment of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Asli MeteDepartment of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Jeroen P J SaeijDepartment of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, California, USA jsaeij@ucdavis.edu.
University of California, Davis · USMassachusetts Institute of Technology · USUniversity of Edinburgh · GB

Funding

Toxoplasma strain-specific modulation of mouse immune cellsR01AI080621 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SAEIJ, JEROEN · 2009 to 2018
$3.6M
Investigating the role of inflammasome activation in the control of T. gondiiF31AI104170 · NIAID · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI CIRELLI, KIMBERLY · 2013 to 2015
$124k
NIAID NIH HHS F31 AI104170NIAID NIH HHS R01 AI080621Wellcome Trust
6 · The paper itself

Abstract

Upon invasion of Lewis rat macrophages,

Indexed as

Host-Pathogen InteractionsPyroptosisAnimalsCells, CulturedCell SurvivalDNA Mutational AnalysisGene DeletionMacrophagesMutagenesisProtozoan ProteinsRats, Inbred F344Rats, Inbred LewToxoplasmaWhole Genome SequencingProtozoan ProteinsDense granule proteinsmacrophagesNLRP1 inflammasomespyroptosisToxoplasma gondii

Identifiers

PMID30622189
PMCPMC6325250
OpenAlexW2910441071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.