Evidence map›Paper›PMID 30622184›Full record

ArticlemBio2019

Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by Candida albicans Hyphae.

Ona Rogiers, Ulrika C Frising, Soňa Kucharíková, Mary Ann Jabra-Rizk, Geert van Loo, Patrick Van Dijck, Andy Wullaert

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
8.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 101 citations in OpenAlex.

  1. The gasdermin family: from pyroptosis mechanisms to therapeutic targets.Signal transduction and targeted therapy · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. The pathogenicity and future treatment strategies ofFrontiers in cellular and infection microbiology · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Host targets of candidalysin.PLoS pathogens · 2025
    Review
  16. Review
  17. Candida albicans: the current status regarding vaginal infections.Applied microbiology and biotechnology · 2025
    Review
  18. Review
  19. Review
  20. Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Ona RogiersVIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Ulrika C FrisingDepartment of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Soňa KucharíkováVIB-KU Leuven Center for Microbiology, Leuven, Belgium.
Mary Ann Jabra-RizkDepartment of Microbiology and Immunology, School of Medicine, University of Maryland, Baltimore, Maryland, USA.
Geert van LooVIB-UGent Center for Inflammation Research, VIB, Ghent, Belgium.
Patrick Van DijckVIB-KU Leuven Center for Microbiology, Leuven, Belgium patrick.vandijck@kuleuven.vib.be andy.wullaert@ugent.be.ORCID 0000-0002-1542-897X
Andy WullaertDepartment of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium patrick.vandijck@kuleuven.vib.be andy.wullaert@ugent.be.ORCID 0000-0001-5012-654X
Ghent University Hospital · BEVIB-KU Leuven Center for Microbiology · BEGhent University · BEUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Host-Pathogen InteractionsAnimalsCandida albicansCells, CulturedFungal ProteinsHyphaeInflammasomesInterleukin-1betaMacrophagesMice, Inbred C57BLNLR Family, Pyrin Domain-Containing 3 ProteinECE1 protein, Candida albicansFungal ProteinsInflammasomesInterleukin-1betaNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanCandida albicanscandidalysininflammasomeNLRP3primary macrophages

Identifiers

PMID30622184
PMCPMC6325245
OpenAlexW2910595122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.